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2539838 cdc23

2539838

cdc23

MCM-associated protein Mcm10

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition MCM-associated protein Mcm10

研究结论

Date Results Publications
2019-11-02 10:36:00 A novel DNA strand-specific 'imprint', installed during DNA replication at the mating-type locus (mat1), imparts competence for cell type inter-conversion to one of the two chromosome replicas; results, while confirming the ribonucleotide nature of the imprint suggest the possibility of a direct role of Mcm10/Cdc23 in installing it in cooperation with Polalpha and Swi1 30759238
2016-12-17 11:20:00 Data collection at lambda = 2.69 A (4.6 keV) allowed the crystal structure determination by sulfur SAD phasing of Cdc23(Nterm), a subunit of the multimeric anaphase-promoting complex (APC/C). At this energy, Cdc23(Nterm) has an expected Bijvoet ratio<|Fanom|>/of 2.2%, with 282 residues, including six cysteines and five methionine residues, and two molecules in the asymmetric unit (65.4 kDa; 12 Cys and ten Met residu... 26960127
2010-01-21 00:00:00 The C terminus of Mcm10p synthesized RNA, but less efficiently than the full-length protein at low rNTP levels; primase activity of Mcm10p may be essential for cell viability 16720577
2010-01-21 00:00:00 The interaction of Mcm10p/Cdc23p with the DNA polymerase alpha-primase complex, its binding to single-stranded DNA, and its activation of the polymerase complex together contribute to its role in the elongation phase of DNA replication. [mcm10] 14766746

名称对应

Type IDs
Synonymous mcm10
Gene
UniProtKB-ID: MCM10_SCHPO
UniprotKB: O42709
UniParc: UPI0000127228
EMBL: AJ224944, CU329671, AB011244
EnsemblGenome: SPBC1347.10
KO: spo:SPBC1347.10
Nucleutide sequences
EMBL-CDS: CAB37441.1, BAA24935.1, CAA12235.1
Gene_ORFName: SPBC1347.10
EnsemblGenome_TRS: SPBC1347.10.1
Protein sequencees
EnsemblGenome_PRO: SPBC1347.10.1:pep
RefSeq: NP_596702.1
Others
UniRef100: UniRef100_O42709
UniRef90: UniRef90_O42709
UniRef50: UniRef50_O42709

全选

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