Type | Description |
---|---|
Definition | CCAAT-binding factor complex subunit Php4 |
Date | Results | Publications |
---|---|---|
2019-06-17 01:03:00 | Study used a pan-S. pombe microarray to study the transcriptional response to iron starvation and identified 86 genes that exhibit php4+-dependent changes on a genome-wide scale. | 18223116 |
2017-12-30 12:02:00 | Study aimed to biochemically define these protein-protein and protein-metal interactions. Grx4 was found to bind a [2Fe-2S] cluster with spectroscopic features similar to other CGFS glutaredoxins. Grx4 and Php4 also copurify as a complex with a [2Fe-2S] cluster that is spectroscopically distinct from the cluster on Grx4these results show that Grx4 controls Php4 function through binding of a bridging [2Fe-2S] cluster. | 28725905 |
2016-01-02 11:41:00 | Grx4 independently governs the Php4 and Fep1 repressors through metal transfer. total or partial disassembly of the Grx4-Fra2 cluster actively participates in iron-containing Fep1 activation | 25806539 |
2015-12-26 11:39:00 | Further analysis by pull-down experiments revealed that Php4 is a cargo of the karyopherins Imp1, Cut15 and Sal3. | 25330182 |
2010-01-21 00:00:00 | Grx4 and Crm1 are novel components involved in the mechanism by which Php4 is inactivated by iron in a Fep1-independent manner. | 19502236 |
Type | IDs |
---|---|
Synonymous | SPBP16F5.09c |
Gene |
UniProtKB-ID:
PHP4_SCHPO
UniprotKB:
O14318
UniParc:
UPI000013A26A
EMBL:
CU329671
EnsemblGenome:
SPBC16E9.01c
KO:
spo:SPBC16E9.01c
|
Nucleutide sequences |
EMBL-CDS:
CAC08548.1
Gene_ORFName:
SPBC16E9.01c,
SPBP16F5.09c
EnsemblGenome_TRS:
SPBC16E9.01c.1
|
Protein sequencees |
EnsemblGenome_PRO:
SPBC16E9.01c.1:pep
RefSeq:
NP_595783.2
|
Others |
UniRef100:
UniRef100_O14318
UniRef90:
UniRef90_O14318
UniRef50:
UniRef50_O14318
|
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Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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