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2539644 php4

2539644

php4

CCAAT-binding factor complex subunit Php4

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition CCAAT-binding factor complex subunit Php4

研究结论

Date Results Publications
2019-06-17 01:03:00 Study used a pan-S. pombe microarray to study the transcriptional response to iron starvation and identified 86 genes that exhibit php4+-dependent changes on a genome-wide scale. 18223116
2017-12-30 12:02:00 Study aimed to biochemically define these protein-protein and protein-metal interactions. Grx4 was found to bind a [2Fe-2S] cluster with spectroscopic features similar to other CGFS glutaredoxins. Grx4 and Php4 also copurify as a complex with a [2Fe-2S] cluster that is spectroscopically distinct from the cluster on Grx4these results show that Grx4 controls Php4 function through binding of a bridging [2Fe-2S] cluster. 28725905
2016-01-02 11:41:00 Grx4 independently governs the Php4 and Fep1 repressors through metal transfer. total or partial disassembly of the Grx4-Fra2 cluster actively participates in iron-containing Fep1 activation 25806539
2015-12-26 11:39:00 Further analysis by pull-down experiments revealed that Php4 is a cargo of the karyopherins Imp1, Cut15 and Sal3. 25330182
2010-01-21 00:00:00 Grx4 and Crm1 are novel components involved in the mechanism by which Php4 is inactivated by iron in a Fep1-independent manner. 19502236

名称对应

Type IDs
Synonymous SPBP16F5.09c
Gene
UniProtKB-ID: PHP4_SCHPO
UniprotKB: O14318
UniParc: UPI000013A26A
EMBL: CU329671
EnsemblGenome: SPBC16E9.01c
KO: spo:SPBC16E9.01c
Nucleutide sequences
EMBL-CDS: CAC08548.1
Gene_ORFName: SPBC16E9.01c, SPBP16F5.09c
EnsemblGenome_TRS: SPBC16E9.01c.1
Protein sequencees
EnsemblGenome_PRO: SPBC16E9.01c.1:pep
RefSeq: NP_595783.2
Others
UniRef100: UniRef100_O14318
UniRef90: UniRef90_O14318
UniRef50: UniRef50_O14318

全选

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