| Type | Description |
|---|---|
| Definition | YTH family RNA-binding protein Mmi1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 10:11:00 | Interaction of S. pombe Mmi1 with the nuclear exosome is mediated by a complex termed MTREC (Mtl1-Red1 core) or NURS (nuclear RNA silencing) that is composed of a conserved zinc-finger protein, Red1, and an RNA helicase, Mtl1. Physical interaction between Mmi1 and the nuclear exosome depends on Red1. Study findings shed light on the target recognition mechanisms of post-transcriptional regulation. | 32012158 |
| 2019-08-12 01:04:00 | The authors propose that nuclear foci formed by Mmi1 are not only the site of RNA degradation, but also of sequestration of meiotic transcripts from the translation machinery. | 29424342 |
| 2019-03-23 11:23:00 | Study suggests that at meiotic initiation, Mei2 may sequester rep2 mRNA to help allow pre-meiotic S, and then may bind both meiRNA and mmi1 mRNA to inactivate Mmi1 at two levels, the protein level and also the mRNA level, allowing meiosis. | 30257894 |
| 2019-02-23 10:57:00 | Study discover that an important function of Mmi1 in promoting non-canonical transcription termination at meiotic genes, and in preventing lncRNAs from invading and repressing adjacent genes, is not dependent upon its association with Erh1. | 30651569 |
| 2019-01-26 11:09:00 | This study reports that an N-terminal extension in mmi1 that is proximal to the YTH domain enhances RNA binding. Using X-ray crystallography, NMR, and biophysical methods, the study shows that this low-complexity region in mmi1 becomes more ordered upon RNA binding. | 29695507 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MMI1_SCHPO
UniprotKB:
O74958
UniParc:
UPI0001B062C2
EMBL:
CU329672
EnsemblGenome:
SPCC736.12c
KO:
spo:SPCC736.12c
|
| Nucleutide sequences |
EMBL-CDS:
CAA19276.3
Gene_ORFName:
SPCC736.12c
EnsemblGenome_TRS:
SPCC736.12c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPCC736.12c.1:pep
RefSeq:
NP_587783.2
|
| Others |
UniRef100:
UniRef100_O74958
UniRef90:
UniRef90_O74958
UniRef50:
UniRef50_O74958
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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