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253943 YTHDF3

253943

YTHDF3

YTH N6-methyladenosine RNA binding protein 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition YTH N6-methyladenosine RNA binding protein 3

研究结论

Date Results Publications
2020-11-21 13:12:00 m(6)A-binding YTHDF proteins promote stress granule formation. 32451507
2020-04-25 12:38:00 Abundance of N-6-methyladenosine and expression of VIRMA/YTHDF3 were different among testicular germ cell tumors subtypes, with higher levels in seminomas (SEs), suggesting a contribution to SE phenotype maintenance. 30866959
2017-12-16 11:38:00 These results indicate that together with YTHDF1 and YTHDF2, YTHDF3 plays critical roles to accelerate metabolism of N(6)-methyladenosine -modified mRNAs in the cytoplasm. 28106072
2017-12-02 10:28:00 The authors found that the overexpression of YTHDF proteins in cells inhibited HIV-1 infection mainly by decreasing HIV-1 reverse transcription, while knockdown of YTHDF1-3 in cells had the opposite effects. Moreover, silencing the N(6)-methyladenosine writers decreased HIV-1 Gag protein expression in virus-producing cells, while silencing the N(6)-methyladenosine erasers increased Gag expression. 27371828
2013-04-22 11:42:00 Includes a multi-species analysis of YTHDF family members. 20463905

名称对应

Type IDs
Gene
UniProtKB-ID: YTHD3_HUMAN, A0A024R7W5_HUMAN, B4DPX9_HUMAN, Q658Z6_HUMAN, A0A087WY31_HUMAN, Q8N3V9_HUMAN, Q8NA80_HUMAN
UniprotKB: Q7Z739, A0A024R7W5, B4DPX9, Q658Z6, A0A087WY31, Q8N3V9, Q8NA80
UniParc: UPI00004402F7, UPI00004402E8, UPI0000D47239, UPI00017A77F8, UPI0002D13FA3, UPI0000071B28, UPI00001A3E7E
EMBL: BC052970, AC011978, CH471068, AK093081, AK127574, AL831816, BX537996, AK298544, AL832005, KF459652, AL832335
Ensembl: ENSG00000185728
KO: hsa:253943
Nucleutide sequences
EMBL-CDS: BAG54526.1, AAH52970.1, EAW86867.1, CAH56224.1, CAH56480.1, EAW86864.1, EAW86866.1, EAW86865.1, BAG60741.1, CAH56223.1, CAD38530.2, BAC04046.1
Gene_ORFName: hCG_41077
Ensembl_TRS: ENST00000539294, ENST00000621890, ENST00000617200, ENST00000623280, ENST00000621413, ENST00000621820
Protein sequencees
Ensembl_PRO: ENSP00000473496, ENSP00000478825, ENSP00000481497, ENSP00000485046, ENSP00000478490, ENSP00000481476
RefSeq: XP_011515812.1, NP_001264746.1, NP_001264745.1, NP_001264744.1, NP_689971.4, XP_011515811.1, NP_001264742.1, NP_001264747.1, NP_001264743.1
Others
UniRef100: UniRef100_Q8N3V9, UniRef100_B4DPX9, UniRef100_Q8NA80, UniRef100_Q658Z6, UniRef100_Q7Z739, UniRef100_A0A087WY31, UniRef100_A0A024R7W5
UniRef90: UniRef90_Q658Z6, UniRef90_A0A3M0KQA9, UniRef90_Q7Z739
UniRef50: UniRef50_Q7Z739, UniRef50_A0A096MUC5, UniRef50_Q9Y5A9
UniGene: Hs.491861
CCDS: CCDS75747.1

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