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2539219 mad3

2539219

mad3

mitotic spindle checkpoint protein Mad3

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition mitotic spindle checkpoint protein Mad3

研究结论

Date Results Publications
2020-07-11 10:58:00 The Bub1 TPR domain is both necessary and sufficient to bind and recruit Mad3. 31257143
2012-08-18 10:18:00 A kinase-dead allele of the fission yeast MPS1 homolog (Mph1) is checkpoint defective and levels of anaphase promoting complex-associated Mad2 and Mad3 are dramatically reduced in this mutant. 22281223
2010-01-21 00:00:00 the Mad3 KEN box is a critical mediator of Cdc20-APC/C inhibition, without which neither Mad3 nor Mad2 can associate with the APC/C or inhibit anaphase onset 18556659
2010-01-21 00:00:00 Bub1p-A78V is defective in both nuclear accumulation and kinetochore targeting; a threshold level of nuclear Bub1p is necessary for the nuclear accumulation of Bub3p and Mad3p 15525673

名称对应

Type IDs
Synonymous SPCC895.02
Gene
UniProtKB-ID: MAD3_SCHPO
UniprotKB: O59767
UniParc: UPI000012EB18
EMBL: CU329672
EnsemblGenome: SPCC1795.01c
KO: spo:SPCC1795.01c
Nucleutide sequences
EMBL-CDS: CAA18636.1
Gene_ORFName: SPCC1795.01c, SPCC895.02
EnsemblGenome_TRS: SPCC1795.01c.1
Protein sequencees
EnsemblGenome_PRO: SPCC1795.01c.1:pep
RefSeq: NP_588043.2
Others
UniRef100: UniRef100_O59767
UniRef90: UniRef90_O59767
UniRef50: UniRef50_O59767

全选

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研究热度

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