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2539209 tel1

2539209

tel1

ATM checkpoint kinase

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition ATM checkpoint kinase

研究结论

Date Results Publications
2018-09-29 11:54:00 The structure suggests that ataxia-telangiectasia mutated protein (ATM/Tel1) dimer interface and the consecutive HEAT repeats inhibit the binding of kinase substrates and regulators by steric hindrance. 27229179
2015-03-28 11:11:00 It is a DNA damage sensor kinases and plays a roll in telomere maintenance. 25675824
2012-02-04 11:33:00 Tel1(ATM)/Rad3(ATR)-dependent Ccq1 Thr93 phosphorylation is a critical regulator of telomere maintenance in fission yeast. 22101932
2010-05-10 12:01:00 The N-terminus of Nbs1 contributes to the recruitment of Rad3(ATR)-Rad26(ATRIP) to telomeres. 20140190
2010-01-21 00:00:00 Tel1 and Rad3 are required for both protection of telomeres against recombination and promotion of telomerase recruitment. 19714219

名称对应

Type IDs
Gene
UniProtKB-ID: ATM_SCHPO
UniprotKB: O74630
UniParc: UPI000006AF78
EMBL: CU329672, AB001995
EnsemblGenome: SPCC23B6.03c
KO: spo:SPCC23B6.03c
Nucleutide sequences
EMBL-CDS: CAB51562.1, BAA33817.1
Gene_ORFName: SPCC23B6.03c
EnsemblGenome_TRS: SPCC23B6.03c.1
Protein sequencees
EnsemblGenome_PRO: SPCC23B6.03c.1:pep
RefSeq: NP_588126.1
Others
UniRef100: UniRef100_O74630
UniRef90: UniRef90_O74630
UniRef50: UniRef50_O74630

全选

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研究热度

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