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2539123 wee1

2539123

wee1

protein kinase Wee1

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition protein kinase Wee1

研究结论

Date Results Publications
2020-06-27 11:53:00 Authors propose a two-step model for inhibition of Wee1 by Cdr1 and Cdr2 at nodes. 31644361
2017-10-02 01:04:00 Regulation of Wee1 localization around the spindle pole body during the G2/M transition is important for proper mitotic entry and progression. 21233285
2017-03-11 11:02:00 in fission yeast Wee1 is the major inhibitory kinase regulating CDK activity in S phase. 26918805
2016-12-17 11:48:00 This cell cycle arrest is dependent on the Wee1 tyrosine kinase inhibiting the key cell cycle regulator, CDK1/Cdc2. Mutant cells lacking Wee1 are not arrested at G2 upon glucose limitation and lose viability faster than the wild-type cells under glucose-depleted quiescent conditions, suggesting that this cell cycle arrest is required for extension of chronological lifespan 26804466
2016-06-04 10:18:00 Wee1 phosphorylates Cdc2 Tyr15 which leads to replication slowdown in the fission yeast under nitrosative stress. 26006103

名称对应

Type IDs
Gene
UniProtKB-ID: WEE1_SCHPO
UniprotKB: P07527
UniParc: UPI0000138EF6
EMBL: M16508, CU329672, AB027900
EnsemblGenome: SPCC18B5.03
KO: spo:SPCC18B5.03
Nucleutide sequences
EMBL-CDS: AAA35354.1, CAB52150.1, BAA87204.1
Gene_ORFName: SPCC18B5.03
EnsemblGenome_TRS: SPCC18B5.03.1
Protein sequencees
EnsemblGenome_PRO: SPCC18B5.03.1:pep
RefSeq: NP_587933.1
Others
UniRef100: UniRef100_P07527
UniRef90: UniRef90_P07527
UniRef50: UniRef50_P07527

全选

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研究热度

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