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2539087 chk1

2539087

chk1

protein kinase Chk1

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition protein kinase Chk1

研究结论

Date Results Publications
2017-05-27 11:43:00 chk1- and wat1-null mutants exhibit conditional synthetic lethality. 27683273
2017-04-01 11:00:00 The isolation of a mutant allele of rna14 in Schizosaccharomyces pombe has been reported that exhibits reduction in protein level of Chk1 at the nonpermissive temperature, primarily due to the defects in posttranscriptional processing. 27350684
2014-11-22 10:57:00 Rad4 mainly functions as a scaffold protein in the Chk1, not the Cds1(CHK2 in humans), checkpoint pathway. It plays a minor role or is functionally redundant with an unknown factor in Rad3 activation. 24663817
2014-11-08 11:54:00 The combination of wat1-17 with the chk1 deletion aggravates the defects in the maintenance of fungal genome ploidy. 24586893
2013-09-21 13:15:00 study describes an analysis of a kinase-associated 1 domain in the C-terminus of Chk1, plus an additional highly conserved motif present in an unique C-terminal extension, both of which are required for Chk1 activation; presence of these motifs provides a rationale as to the dual nature of the regulatory domain 23422000

名称对应

Type IDs
Synonymous rad27
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_001342786.1
Others

全选

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研究热度

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