| Type | Description |
|---|---|
| Definition | activating transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-14 10:13:00 | Data suggest that heat stress enhances ovarian levels of Hsp70 and affects Erk1/2 and Atf3 phosphorylation levels, but not c-Akt activation/phosphorylation, in pseudo-pregnant rats during luteal regression induced by cloprostenol, a prostaglandin F2alpha analog. (Hsp70 = heat shock 70 kDa protein; Erk = extracellular signal-regulated kinase; Atf3 = activating transcription factor-3; c-Akt = proto-oncogene protein c-Akt) | 27169499 |
| 2018-05-12 11:13:00 | ATF3 was highly expressed in the livers of ZDF rats. Insulin resistance and hepatic steatosis were associated with increased ATF3 expression and decreased fatty acid oxidation via mitochondrial dysfunction and were attenuated by in vivo ATF3 silencing. Knockdown of ATF3 also ameliorated glucose intolerance, impaired insulin action, and inflammatory responses in ZDF rats. | 28365312 |
| 2017-09-30 12:00:00 | sublytic C5b-9-induced activation of Egr-1/p300-ATF3/Gadd45 axis plays a critical role in glomerular mesangial cells apoptosis in Thy-1N rats. | 27190312 |
| 2017-05-06 10:30:00 | The cellular injury/stress response induced in sensory neurons by tissue damage and indicated by ATF3 expression is positioned to contribute to pain which can occur after tissue damage. | 27264359 |
| 2016-04-16 10:47:00 | Heme oxygenase-1/signal transducer and activator of transcription 3 signaling plays a critical role in propofol-mediated amelioration of hyperglycemia-induced cardiomyocyte hypertrophy and apoptosis. | 24810525 |
| Type | IDs |
|---|---|
| Synonymous | LRF-1, LRFI |
| Gene |
UniProtKB-ID:
ATF3_RAT
UniprotKB:
P29596
UniParc:
UPI000012622F
EMBL:
M63282,
BC078903
Ensembl:
ENSRNOG00000003745
KO:
rno:25389
|
| Nucleutide sequences |
EMBL-CDS:
AAH78903.1,
AAA41542.1
Ensembl_TRS:
ENSRNOT00000089841,
ENSRNOT00000005085
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000005085,
ENSRNOP00000071188
RefSeq:
NP_037044.1
|
| Others |
UniRef100:
UniRef100_P29596
UniRef90:
UniRef90_P29596
UniRef50:
UniRef50_P29596
UniGene:
Rn.9664
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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