| Type | Description |
|---|---|
| Definition | zinc finger DHHC-type containing 20 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 11:46:00 | crystal structure determined; active site resides at the membrane-cytosol interface; acyl chain binds in a cavity formed by the transmembrane domain; propose a mechanism for acyl chain-length selectivity in DHHC enzymes on the basis of cavity mutants with preferences for shorter and longer acyl chains | 29326245 |
| 2017-08-05 11:02:00 | Targeting of a peripheral modulator of EGFR signaling, DHHC20, causes a loss of signal regulation and susceptibility to EGFR inhibitor-induced cell death. | 27153536 |
| 2010-10-29 16:55:00 | DHHC20 is a human N-terminal-myristoyl-directed palmitoyl acyltransferase involved in cellular transformation, that may play a role in cancer. | 20334580 |
| Type | IDs |
|---|---|
| Synonymous | 4933421L13Rik, DHHC-20, DHHC20 |
| Gene |
UniProtKB-ID:
ZDH20_HUMAN,
B4DRN8_HUMAN
UniprotKB:
Q5W0Z9,
B4DRN8
UniParc:
UPI000035082F,
UPI000066218B,
UPI00003B90E3,
UPI000045881B,
UPI00017A7A28
EMBL:
BC067898,
BC110517,
CH471075,
BC034944,
AL136219,
AK299354,
BC050367
Ensembl:
ENSG00000180776
KO:
hsa:253832
|
| Nucleutide sequences |
EMBL-CDS:
AAH50367.2,
AAH67898.1,
EAX08309.1,
AAH34944.1,
AAI10518.1,
BAG61350.1
Ensembl_TRS:
ENST00000382466,
ENST00000400590,
ENST00000415724,
ENST00000320220,
ENST00000542645
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383433,
ENSP00000371905,
ENSP00000401232,
ENSP00000313583,
ENSP00000443236
RefSeq:
NP_694983.2,
NP_001316988.1,
XP_006719859.1,
XP_016876016.1,
XP_006719860.1,
NP_001273567.1,
XP_016876015.1,
XP_011533332.1,
XP_016876014.1
|
| Others |
UniRef100:
UniRef100_Q5W0Z9,
UniRef100_B4DRN8
UniRef90:
UniRef90_B4DRN8,
UniRef90_Q5W0Z9
UniRef50:
UniRef50_Q5W0Z9
UniGene:
Hs.564611
CCDS:
CCDS45017.1,
CCDS81758.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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