| Type | Description |
|---|---|
| Definition | methionine sulfoxide reductase B3 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:46:00 | MSRB3 promotes the progression of clear cell renal cell carcinoma via regulating endoplasmic reticulum stress. | 31889586 |
| 2020-06-27 12:35:00 | individuals with MSRB3 rs61921502 minor allele had increased odds for brain infarcts on MRI compared to those with no minor allele | 30775993 |
| 2018-09-22 10:44:00 | we characterise the mammalian enzyme Msr B3. There are two splice variants of this enzyme that differ only in their N-terminal signal sequence, which directs the protein to either the endoplasmic reticulum (ER) or mitochondria | 29420254 |
| 2018-05-12 11:52:00 | This characterization of GWAS-implicated MSRB3 protein expression in human hippocampus suggests that patterns of neuronal and vascular MsrB3 protein expression reflect or underlie pathology associated with Alzheimer disease. | 28777754 |
| 2017-08-19 12:38:00 | Oncogene induction in differentiated cells induces massive DNA damage, mammary stem cells are resistant, owing to a preemptive program driven by ZEB1 and MSRB3. The prevention of oncogene-induced DNA damage precludes induction of the oncosuppressive p53-dependent DNA-damage response, thereby increasing stem cells' intrinsic susceptibility to malignant transformation. | 28394329 |
| Type | IDs |
|---|---|
| Synonymous | DFNB74 |
| Gene |
UniProtKB-ID:
MSRB3_HUMAN
UniprotKB:
Q8IXL7
UniParc:
UPI0000074381,
UPI0000051E32
EMBL:
AK293084,
BX648776,
BC040053,
AY358229,
AK316365,
AK299065
Ensembl:
ENSG00000174099
KO:
hsa:253827
|
| Nucleutide sequences |
EMBL-CDS:
CAI46018.1,
AAQ88596.1,
BAG61131.1,
BAF85773.1,
BAH14736.1,
AAH40053.1
Gene_ORFName:
UNQ1965/PRO4487
Ensembl_TRS:
ENST00000308259,
ENST00000355192,
ENST00000642404,
ENST00000646299,
ENST00000535664,
ENST00000642411,
ENST00000614640
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441650,
ENSP00000347324,
ENSP00000494941,
ENSP00000312274,
ENSP00000496008,
ENSP00000481483,
ENSP00000494265
RefSeq:
XP_024304689.1,
NP_001180390.1,
XP_024304690.1,
NP_001026849.1,
NP_001180389.1,
XP_024304686.1,
XP_024304688.1,
XP_024304687.1,
NP_932346.1
|
| Others |
UniRef100:
UniRef100_Q8IXL7
UniRef90:
UniRef90_Q8IXL7
UniRef50:
UniRef50_Q8IXL7
UniGene:
Hs.339024
CCDS:
CCDS31853.1,
CCDS8973.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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