| Type | Description |
|---|---|
| Definition | ceramide synthase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:56:00 | Long noncoding RNA CERS6-AS1 functions as a malignancy promoter in breast cancer by binding to IGF2BP3 to enhance the stability of CERS6 mRNA. | 31701672 |
| 2019-12-21 10:04:00 | These associations were successfully replicated in an independent collection of Indigenous Australian T2D cases and controls. These SNPs all lie within the gene encoding ceramide synthase 6 (CERS6) and thus may regulate ceramide synthesis. | 31012404 |
| 2019-11-16 10:56:00 | CERS6 interferes with Fas-Fas-associated protein with death domain death-inducing signaling complex assembly. CERS6 may serve as a biomarker in determining the effectiveness of anticancer agents acting via the extrinsic pathway in T-cell acute lymphoblastic leukemia. | 30206207 |
| 2019-10-05 12:34:00 | CerS6 could mediate an effective response to cisplatin in chemoresistant oral squamous cell carcinoma. | 30054909 |
| 2019-06-01 10:12:00 | The human CERS6 gene promoter harbors a large CpG island (94 CpGs) and multiple transcription factor binding sites (TFBS), which support precise transcriptional regulation and signaling functions. Additional regulation is conferred by 15 microRNA (miRNA) target sites identified in the CERS6 3'-UTR region | 30297675 |
| Type | IDs |
|---|---|
| Synonymous | CERS5, LASS6 |
| Gene |
UniProtKB-ID:
CERS6_HUMAN
UniprotKB:
Q6ZMG9
UniParc:
UPI000020902F,
UPI000020902D
EMBL:
AC009475,
BC030800,
AC019086,
BC109284,
AC097453,
AK172775,
BC109285
Ensembl:
ENSG00000172292
KO:
hsa:253782
|
| Nucleutide sequences |
EMBL-CDS:
AAI09286.1,
AAI09285.1,
AAH30800.2,
BAD18757.1
Ensembl_TRS:
ENST00000392687,
ENST00000305747
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000306579,
ENSP00000376453
RefSeq:
XP_024308549.1,
XP_005246497.1,
XP_024308548.1,
NP_982288.1,
NP_001243055.1,
XP_016859238.1
|
| Others |
UniRef100:
UniRef100_Q6ZMG9
UniRef90:
UniRef90_Q6ZMG9
UniRef50:
UniRef50_Q6ZMG9
UniGene:
Hs.506829,
Hs.743222
CCDS:
CCDS58734.1,
CCDS2228.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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