| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2016-03-26 10:46:00 | Our findings reveal a novel mechanism of GRK3 control of the dopamine receptor signaling and the role of Gq in LID. | 26043205 |
| 2014-02-08 10:13:00 | the loss of GRK3-mediated regulation of CXCL12/CXCR4 signaling contributes to some, but not all, of the complete WHIM phenotype and that GRK3 inhibition may be beneficial in the treatment of inflammatory arthritis. | 23935208 |
| 2011-09-10 10:11:00 | We suggest that reduced stress resilience after TSS may be related to oxidative stress, depletion of GRK3 and impaired regulation of alpha(2A)-AR and CRF(1)-R in LC. | 21333691 |
| 2010-01-21 00:00:00 | Substrate specificity of Grk3 at cardiac myocyte receptors provides basis for distinct role in regulation of myocardial function. | 17573483 |
| 2010-01-21 00:00:00 | CRF selectively up-regulates GRK3 expression via an ERK1/2-mediated mechanism accompanied by the activation of Sp-1 and Ap-2 transcription factors. | 17583697 |
| Type | IDs |
|---|---|
| Synonymous | Adrbk2 |
| Gene |
UniProtKB-ID:
ARBK2_RAT
UniprotKB:
P26819
UniParc:
UPI0000050ED7
EMBL:
M87855
KO:
rno:25372
|
| Nucleutide sequences |
EMBL-CDS:
AAA40803.1
|
| Protein sequencees |
RefSeq:
NP_037029.2,
XP_017453761.1
|
| Others |
UniRef100:
UniRef100_P26819
UniRef90:
UniRef90_P26819
UniRef50:
UniRef50_P26817
UniGene:
Rn.9861
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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