| Type | Description |
|---|---|
| Definition | interferon alpha inducible protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:20:00 | G1P3-induced have a direct role in migratory structure formation and nuclear gene expression to promote breast cancer cell metastasis. Therefore, interrupting mitochondrial functions of G1P3 may improve clinical outcomes in breast cancer patients | 29899394 |
| 2019-06-01 12:28:00 | Flavivirus replication at the ER is targeted by the interferon (IFN) response. Interferon alpha inducible protein 6 (IFI6) is an endoplasmic reticulum (ER)-localized integral membrane effector that is stabilized through interactions with the ER-resident heat shock protein 70 chaperone BiP. IFI6 prophylactically protects uninfected cells by preventing the formation of virus-induced ER membrane invaginations. | 30224801 |
| 2018-07-03 11:26:00 | Consequent to its localisation on inner-mitochondrial membrane, were higher in G1P3-expressing cells (MCF-7G1P3). This study identified that G1P3-induced mtduanyu1670 have a direct role in migratory structure formation and nuclear gene expression to promote breast cancer cell metastasis. | 29899394 |
| 2018-04-14 11:20:00 | Data suggest that p7 is a critical immune evasion protein that suppresses the antiviral interferon function by counteracting the function of IFI6-16. | 28159892 |
| 2017-05-20 11:52:00 | In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1, TLR3, OAS1, EIF2AK2, HLA-E, IFI6, and showed higher expression in the islet core compared with the peri-islet area containing the surrounding immune cells | 27422384 |
| Type | IDs |
|---|---|
| Synonymous | 6-16, FAM14C, G1P3, IFI-6-16, IFI616 |
| Gene |
UniProtKB-ID:
IFI6_HUMAN,
A0A348GSI1_HUMAN
UniprotKB:
P09912,
A0A348GSI1
UniParc:
UPI000002ABE5,
UPI000002ABE4,
UPI000012D679
EMBL:
BC015603,
AL445490,
BC011601,
X02492,
AK314488,
U22970,
BN000257,
CH471059,
LC420313,
BT006850
Ensembl:
ENSG00000126709
KO:
hsa:2537
|
| Nucleutide sequences |
EMBL-CDS:
CAA26322.1,
CAE12275.1,
AAC50160.1,
AAH11601.1,
AAC50159.1,
BAG37089.1,
AAH15603.1,
EAX07744.1,
EAX07745.1,
AAP35496.1,
AAC50161.1,
EAX07746.1,
BBG06130.1
Ensembl_TRS:
ENST00000362020,
ENST00000339145,
ENST00000361157
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342513,
ENSP00000354736,
ENSP00000355152
RefSeq:
NP_075011.1,
NP_002029.3,
NP_075010.1,
XP_024301975.1
|
| Others |
UniRef100:
UniRef100_P09912
UniRef90:
UniRef90_P09912
UniRef50:
UniRef50_P09912
UniGene:
Hs.523847,
Hs.730125
CCDS:
CCDS307.1,
CCDS306.1,
CCDS308.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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