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253559 CADM2

253559

CADM2

cell adhesion molecule 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell adhesion molecule 2

研究结论

Date Results Publications
2020-10-24 14:05:00 Genetic variation in CADM2 as a link between psychological traits and obesity. 31089183
2020-08-12 14:16:00 The study findings provide independent support for the association of CADM2 SNP rs17518584 with processing speed (and demonstrate association with additional cognitive phenotypes), among cognitively normal elderly individuals with type 2 diabetes. 28797215
2020-03-21 12:31:00 Study identified an association between single nucleotide polymorphisms in CADM2 and Sensation Seeking and Drug Experimentation via single variant, gene- and transcriptome-based analyses; CADM2 has been previously implicated in numerous traits related to risk taking. In addition, we identified an association between variants in CACNA1I and Negative Urgency via single-variant and gene-based analyses. 30718321
2019-09-28 10:33:00 Study provide further support for a role of cell adhesion molecule 2 in aspects of cognitive function, in particular reading and information processing speed, and suggest that this role extends to younger individuals. 30125698
2019-07-06 12:58:00 Study demonstrated that CADM2 was markedly downregulated in human glioma tissues compared with normal brain tissue and glioma cell lines, and the CADM2 expression level was significantly decreased in highgrade glioma tissues. Overexpression of CADM2 inhibited the proliferation of glioma cell proliferation in vitro and in vivo. 30816549

名称对应

Type IDs
Synonymous IGSF4D, NECL3, Necl-3, SynCAM 2, synCAM2
Gene
UniProtKB-ID: CADM2_HUMAN, G3XHN4_HUMAN
UniprotKB: Q8N3J6, G3XHN4
UniParc: UPI0000035DF5, UPI000013F072, UPI00022B83EF, UPI000006DE82, UPI000013F077
EMBL: AL833049, AB646740, AB646739, BC105999, AB646741, AL834270, AB646742, AF538973, AB646743
Ensembl: ENSG00000175161
KO: hsa:253559
Nucleutide sequences
EMBL-CDS: BAK93305.1, BAK93303.1, AAN16368.1, BAK93304.1, AAI06000.1, CAD38945.1, BAK93306.1, CAH56314.1, BAK93302.1
Ensembl_TRS: ENST00000383699, ENST00000407528, ENST00000405615
Protein sequencees
Ensembl_PRO: ENSP00000384193, ENSP00000384575, ENSP00000373200
RefSeq: NP_001161146.1, NP_001243434.1, NP_001243433.1, NP_694854.2, NP_001362896.1, XP_016861552.1, NP_001362893.1, NP_001243432.1, NP_001368893.1, NP_001362890.1, NP_001243431.1, NP_001368892.1, XP_016861551.1, NP_001161147.1, NP_001362889.1, NP_001362897.1
Others
UniRef100: UniRef100_Q8N3J6, UniRef100_G3XHN4
UniRef90: UniRef90_G3XHN4, UniRef90_Q8N3J6
UniRef50: UniRef50_Q8N3J6
UniGene: Hs.164578
CCDS: CCDS33792.1, CCDS54614.1, CCDS54613.1

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