| Type | Description |
|---|---|
| Definition | surfactant protein D |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 10:39:00 | Polydatin significantly reduced the inflammatory mediators and restored the normal values of oxidative and nitrosative stress biomarkers. It also significantly reduced the expression of surfactant-D and UCN as compared to asthma control | 30422021 |
| 2017-12-16 12:04:00 | in acute lung injury, serum level increased from day 5, peaked on day 10, and then gradually decreased until day 28 | 27541374 |
| 2017-08-19 10:38:00 | binds dipalmitoyl-phosphatidylcholine, the major surfactant lipid component, but not phosphatidylinositol; SPD exhibits the opposite preference. Data suggest flexibility in a key surface loop supports distinctive lipid binding of quadruple mutant duanyu1842 (E171D/P175E/R197N/K203D) that introduces SPD-like loop-stabilizing Ca2+ binding site in carbohydrate recognition domain exhibits ligand-binding preferences of SPD. | 28719181 |
| 2013-02-23 10:55:00 | In rat SP-D overexpressed mice, the lipopolysaccharide-induced levels of TNF-alpha and IL-10 in amniotic fluid and fetal serum and the expression of IL-10 in placenta and fetal membranes were significantly different from wild-type mice. | 22892325 |
| 2012-06-23 12:12:00 | Surfactant protein D modulated subpollen particle uptake in a cell type specific way (e.g. greater number of macrophages and epithelial cells, which participated in allergen particle uptake) and led to a decreased secretion of pro-inflammatory cytokines. | 22296755 |
| Type | IDs |
|---|---|
| Synonymous | SP-D, SPD |
| Gene |
UniProtKB-ID:
SFTPD_RAT
UniprotKB:
P35248
UniParc:
UPI0000132804
EMBL:
M81231
KO:
rno:25350
|
| Nucleutide sequences |
EMBL-CDS:
AAA42170.1
|
| Protein sequencees |
RefSeq:
NP_037010.1
|
| Others |
UniRef100:
UniRef100_P35248
UniRef90:
UniRef90_P35248
UniRef50:
UniRef50_P35248
UniGene:
Rn.11348
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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