| Type | Description |
|---|---|
| Definition | frizzled class receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 14:04:00 | FZD2 acts as an oncogene in tongue cancer, promoting cell growth, invasion and migration. | 31595151 |
| 2020-02-01 11:27:00 | Fz2 and Wnt5a, might be involved in human Amyotrophic lateral sclerosis pathology. | 30924074 |
| 2019-04-20 12:22:00 | FZD2 could promote clinically relevant EMT, CD44(+) stem-like properties, and the VM phenotype in HCC involving a potential Hippo signaling pathway-dependent mechanism, and should be considered as a promising therapeutic target for the treatment of HCC. | 30677195 |
| 2019-03-02 11:50:00 | The results indicate that OMOD2 or Robinow syndome-like phenotype can be caused by a heterozygous nonsense FZD2 mutation impairing Wnt signaling. | 29383834 |
| 2018-08-04 10:11:00 | Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway through inhibition of Wnt2 and Fzd2. | 29259372 |
| Type | IDs |
|---|---|
| Synonymous | Fz2, OMOD2, fz-2, fzE2, hFz2 |
| Gene |
UniProtKB-ID:
FZD2_HUMAN,
Q86UZ8_HUMAN
UniprotKB:
Q14332,
Q86UZ8
UniParc:
UPI0000192752,
UPI0000050444
EMBL:
AB017364,
BC052266,
BC113402,
BC113404,
L37882
Ensembl:
ENSG00000180340
KO:
hsa:2535
|
| Nucleutide sequences |
EMBL-CDS:
AAI13405.1,
AAI13403.1,
BAA34667.1,
AAB46397.1,
AAH52266.1
Ensembl_TRS:
ENST00000315323
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000323901
RefSeq:
NP_001457.1
|
| Others |
UniRef100:
UniRef100_Q14332
UniRef90:
UniRef90_Q14332
UniRef50:
UniRef50_Q14332
UniGene:
Hs.142912,
Hs.732654
CCDS:
CCDS11484.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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