| Type | Description |
|---|---|
| Definition | inositol polyphosphate multikinase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:24:00 | Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity. | 33290695 |
| 2020-06-06 13:34:00 | Deletion of IPMK in cell lines and intact mice virtually abolishes lipophagy, promotes liver damage as well as inflammation, and impairs hepatocyte regeneration. | 30840891 |
| 2019-12-21 11:39:00 | rs2790234 and rs6481383 are associated with longevity in women. | 30744060 |
| 2017-11-25 15:28:00 | Data suggest that IPMK exhibits constrained, horseshoe-shaped substrate pocket, formed from an alpha-helix, a 3(10) helix, and a recently evolved tri-proline loop; headgroups of substrates (inositol 4,5-bisphosphate and inositol 1,4,5-trisphosphate) bind in precisely the same orientation, indicative of evolutionary optimization of 3-kinase activities against both substrates. | 28882892 |
| 2017-11-18 12:14:00 | IPMK is a versatile regulator of nuclear signaling events. (Review) | 26682649 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IPMK_HUMAN
UniprotKB:
Q8NFU5
UniParc:
UPI000006FB8E
EMBL:
BK000580,
BC065709,
AF432853
Ensembl:
ENSG00000151151
KO:
hsa:253430
|
| Nucleutide sequences |
EMBL-CDS:
AAM97838.1,
DAA01362.1,
AAH65709.1
Ensembl_TRS:
ENST00000373935
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363046
RefSeq:
NP_689416.1,
XP_016871502.1,
XP_011537867.1
|
| Others |
UniRef100:
UniRef100_Q8NFU5
UniRef90:
UniRef90_Q8NFU5
UniRef50:
UniRef50_Q8NFU5
UniGene:
Hs.30280
CCDS:
CCDS7250.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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