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2534 FYN

2534

FYN

FYN proto-oncogene, Src family tyrosine kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition FYN proto-oncogene, Src family tyrosine kinase

研究结论

Date Results Publications
2021-04-17 13:16:00 FYN is required for ARHGEF16 to promote proliferation and migration in colon cancer cells. 32811808
2021-03-28 19:08:00 Profibrotic epithelial TGF-beta1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN. 33325804
2020-11-28 13:17:00 The phosphorylation of CD147 by Fyn plays a critical role for melanoma cells growth and metastasis. 32291412
2020-11-21 13:25:00 Fyn stimulates the progression of pancreatic cancer via Fyn-GluN2b-AKT axis. 31957823
2020-09-26 13:09:00 Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder. 32929078

名称对应

Type IDs
Synonymous SLK, SYN, p59-FYN
Gene
UniProtKB-ID: FYN_HUMAN
UniprotKB: P06241
UniParc: UPI0000141141, UPI0000087FDD, UPI000006F756
EMBL: M14676, Z97989, S74774, AB451293, CH471051, M14333, AB451426, BC032496
Ensembl: ENSG00000010810
KO: hsa:2534
Nucleutide sequences
EMBL-CDS: EAW48278.1, BAG70240.1, AAA36615.1, EAW48281.1, EAW48283.1, BAG70107.1, EAW48279.1, AAH32496.1, EAW48282.1, AAB33113.2, AAC08285.1
Ensembl_TRS: ENST00000229471, ENST00000368667, ENST00000368678, ENST00000354650, ENST00000368682, ENST00000538466
Protein sequencees
Ensembl_PRO: ENSP00000357667, ENSP00000440646, ENSP00000357671, ENSP00000229471, ENSP00000357656, ENSP00000346671
RefSeq: XP_016866139.1, XP_016866142.1, XP_005266949.1, NP_002028.1, NP_694592.1, NP_001357458.1, XP_016866141.1, XP_016866144.1, XP_016866140.1, NP_694593.1
Others
UniRef100: UniRef100_P06241
UniRef90: UniRef90_P06241
UniRef50: UniRef50_P06241
UniGene: Hs.390567, Hs.664520
CCDS: CCDS5094.1, CCDS5096.1, CCDS5095.1

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