| Type | Description |
|---|---|
| Definition | Janus kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 10:53:00 | treatment downregulated the expression of JAK1, JAK3 and and upregulated cytosolic nuclear factor (NF)kappaB p65 and IkappaB. In conclusion, the results of the present study indicated that curculigoside exhibited significant antiarthritic effects in vivo and in vitro, and the molecular mechanism may be associated with the signaling pathway. | 30664158 |
| 2017-07-15 10:57:00 | JAK3 mediates smooth muscle cell proliferation and survival during injury-induced vascular remodeling. | 28473442 |
| 2016-03-19 10:10:00 | results showed that different JAK3 mutations induce constitutive activation through distinct mechanisms, pointing to specific therapeutic perspectives | 26446793 |
| 2013-12-28 10:10:00 | Inhibition of the Jak3/Stat3 signaling pathway promotes apoptosis in a colon cancer model. | 23514809 |
| 2013-01-26 11:17:00 | Secreted phospholipase PLA-IIA expression is regulated by the nitric oxide pathway in microvascular endothelial cells of the injured brain. | 22788969 |
| Type | IDs |
|---|---|
| Synonymous | RATJAK3 |
| Gene |
UniProtKB-ID:
F1LR79_RAT
UniprotKB:
F1LR79
UniParc:
UPI000019C11E
EMBL:
CH474031,
AABR07024869
Ensembl:
ENSRNOG00000018669
KO:
rno:25326
|
| Nucleutide sequences |
EMBL-CDS:
EDL90762.1,
EDL90763.1,
EDL90761.1
Gene_ORFName:
rCG_38627
Ensembl_TRS:
ENSRNOT00000079784,
ENSRNOT00000025312
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000025312,
ENSRNOP00000071081
RefSeq:
XP_008769286.1,
NP_036987.2,
XP_017455482.1
|
| Others |
UniRef100:
UniRef100_F1LR79
UniRef90:
UniRef90_Q62137
UniRef50:
UniRef50_P52333
UniGene:
Rn.11159
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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