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2532 ACKR1

2532

ACKR1

atypical chemokine receptor 1 (Duffy blood group)

protein-coding

Homo sapiens

基因描述

Type Description
Definition atypical chemokine receptor 1 (Duffy blood group)

研究结论

Date Results Publications
2021-01-09 13:34:00 The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans. 33211774
2020-11-21 13:20:00 Differential interaction between DARC and SDF-1 on erythrocytes and their precursors. 31700087
2020-08-22 15:25:00 Increased frequency of the single nucleotide polymorphism of the DARC/ACKR1 gene associated with ethnic neutropenia in a cohort of European patients with chronic idiopathic neutropenia. 32243614
2020-08-01 15:32:00 Decreased expression of ACKR1 was associated with cervical cancer in comparison to normal cervical tissue. The lower AKCR1 expression levels in cervical tumors correlated with poor prognosis. 32083574
2020-02-01 11:07:00 in an Indian population, DARC 298A carriage appeared to increase the risk of malaria, and of vivax malaria in particular 31551092

名称对应

Type IDs
Synonymous CCBP1, CD234, DARC, DARC/ACKR1, Dfy, FY, GPD, GpFy, WBCQ1
Gene
UniProtKB-ID: ACKR1_HUMAN, Q5Y7A1_HUMAN, Q5Y7A2_HUMAN
UniprotKB: Q16570, Q5Y7A1, Q5Y7A2
UniParc: UPI000013E1B0, UPI000016A110
EMBL: AK291593, DQ181560, JN251907, JN251908, X85785, AM887935, AY663418, DQ181558, MK813894, MN813502, DQ181554, JN251909, DQ181557, DQ181559, MK813892, MN813506, DQ181556, AF030521, MN813523, DQ181562, MK813893, BC017817, MN813507, U01839, AL035403, MN813505, DQ181561, MN813501, LN715170, DQ181567, MK813895, AF055992, S76830, AF100634, MN813503
Ensembl: ENSG00000213088
KO: hsa:2532
Nucleutide sequences
EMBL-CDS: AAH17817.1, AAF02416.1, AAF02415.1, CAA59770.1, AAB33239.1, AAD20435.1, AAC72301.1, AAC50055.1, CAP12644.1, AET81022.1, ABA10419.1, ABA10413.1, AAU47282.1, ABA10422.1, ABA10407.1, ABA10446.1, AET81020.1, AET81017.1, ABA10416.1, ABA10431.1, ABA10425.1, ABA10428.1, QFU95375.1, AET81021.1, QLM06186.1, ABA10412.1, ABA10424.1, QLM06169.1, QFU95376.1, AET81019.1, QLM06168.1, CEL12051.1, ABA10427.1, ABA10430.1, QLM06165.1, QLM06170.1, ABA10421.1, QLM06166.1, ABA10415.1, ABA10445.1, ABA10406.1, AET81018.1, ABA10418.1, AAU47281.1, QFU95374.1, BAF84282.1, QFU95373.1, QLM06164.1
Ensembl_TRS: ENST00000368121, ENST00000537147, ENST00000368122
Protein sequencees
Ensembl_PRO: ENSP00000357103, ENSP00000357104, ENSP00000441985
RefSeq: NP_001116423.1, NP_002027.2
Others
UniRef100: UniRef100_Q5Y7A1, UniRef100_Q16570
UniRef90: UniRef90_Q16570
UniRef50: UniRef50_Q16570
UniGene: Hs.153381
CCDS: CCDS44252.1, CCDS1183.1

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