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25317 Fgf1

25317

Fgf1

fibroblast growth factor 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition fibroblast growth factor 1

研究结论

Date Results Publications
2020-12-19 13:41:00 FGF-1 modulates pancreatic beta-cell functions/metabolism: An in vitro study. 32360543
2018-06-30 10:32:00 FGF1-overexpressed adipose-derived mesenchymal stem induce neuroprotection and functional recovery in a rat stroke model. 28795363
2018-04-28 11:18:00 Suboptimal FGFR activation by a weak FGF1-FGFR dimer is sufficient to evoke a metabolic response, whereas full FGFR activation by stable and sustained dimerization is required to elicit a mitogenic response. 28813681
2018-03-24 11:34:00 This is the first time a comprehensive subset of proteins involved in FGF inhibitory response is defined. We were able to identify a number of targets and specifically discover glycogen synthase kinase3beta (GSK3beta) as a novel key mediator of FGF inhibitory response in chondrocytes. 28298517
2017-05-13 13:42:00 FGF-1 may have preventative and therapeutic effects on TGF-beta1-driven pulmonary fibrosis via inhibiting myofibroblast differentiation, inducing AEC proliferation, regulating TGF-beta1 signalling by controlling TGFbetaR1 expression and degradation, and regulating FGFR1 expression. 27425145

名称对应

Type IDs
Synonymous FGF-1, HBGF-1, HBGF1
Gene
UniProtKB-ID: FGF1_RAT
UniprotKB: P61149
UniParc: UPI0000001AC3
EMBL: X14232
Ensembl: ENSRNOG00000013867
KO: rno:25317
Nucleutide sequences
EMBL-CDS: CAA32448.1
Ensembl_TRS: ENSRNOT00000018577, ENSRNOT00000087408
Protein sequencees
Ensembl_PRO: ENSRNOP00000018577, ENSRNOP00000070685
RefSeq: XP_006254714.1, NP_036978.1, XP_006254713.1, XP_006254712.1
Others
UniRef100: UniRef100_P61148
UniRef90: UniRef90_P61148
UniRef50: UniRef50_P61148
UniGene: Rn.88013

全选

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研究热度

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