| Type | Description |
|---|---|
| Definition | ATP binding cassette subfamily C member 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 12:16:00 | we demonstrate redistribution of intestinal MRP2 between plasma membrane and intracellular membrane in rat jejunum and in Caco-2 cells in response to db-cAMP and estradiol-17beta-D-glucuronide | 29052767 |
| 2018-10-20 10:35:00 | In conclusion, our data supports the hypothesis that isoniazid can induce liver injury via the down-regulation of hepatic efflux transporters BSEP and MRP2, and the SIRT1/FXR pathway may be the primary regulator with regard to the expression of transporters and the biosynthesis of bile acids in the liver. | 30068870 |
| 2018-03-17 11:17:00 | Bile transporters OATP1/MRP2 mRNA expression ratio in liver tissue decreased with dimethylnitrosamine-induced liver injury, model of liver cirrhosis. | 27780379 |
| 2017-10-28 12:10:00 | GLP-2 can prevent down-regulation of intestinal expression and activity of Mrp2 and P-gp in endotoxemic rats. | 28842383 |
| 2017-04-22 10:44:00 | Calculus Bovis administration can alleviate liver injury and up-regulate the expression of BSEP and MRP2 in 17alpha-ethynylestradiol-induced cholestasis by a mechanism that may involve inhibiting the activated PI3K/Akt signaling pathway. | 27237619 |
| Type | IDs |
|---|---|
| Synonymous | Cmoat, Mrp2, cMRP, mrp |
| Gene |
UniProtKB-ID:
MRP2_RAT
UniprotKB:
Q63120
UniParc:
UPI000012F578
EMBL:
D86086,
L49379,
X96393
Ensembl:
ENSRNOG00000046727
KO:
rno:25303
|
| Nucleutide sequences |
EMBL-CDS:
AAC42087.1,
BAA13016.1,
CAA65257.1
Ensembl_TRS:
ENSRNOT00000070861
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000064799
RefSeq:
NP_036965.1
|
| Others |
UniRef100:
UniRef100_Q63120
UniRef90:
UniRef90_Q63120
UniRef50:
UniRef50_Q92887
UniGene:
Rn.10265
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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