| Type | Description |
|---|---|
| Definition | cholinergic receptor nicotinic alpha 7 subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | Lovastatin Differentially Regulates alpha7 and alpha4 Neuronal Nicotinic Acetylcholine Receptor Levels in Rat Hippocampal Neurons. | 33092257 |
| 2020-08-22 15:31:00 | Antagonizing alpha7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition. | 31176021 |
| 2020-08-13 18:50:00 | Eliciting alpha7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling. | 31062470 |
| 2020-07-04 10:48:00 | Microstructural injury-induced alterations of alpha7nAChR in the vulnerable area are significantly correlated with learning and memory dysfunctions after Diffuse Axonal Injury and that augmentation of the alpha7nAChR level by its agonist contributes to the improvement of learning and memory function. | 31398352 |
| 2020-03-21 11:39:00 | Nicotine pre-treatment in primary astrocytes inhibited Abeta aggregation and upregulated endogenous astrocytic Cryab, while the nicotine-mediated neuroprotective effect was reversed by pre-treatment with a selective alpha7 nAChR antagonist. This neuroprotection against Abeta aggregation was suppressed by LY294002, a PI3K inhibitor. Pre-treatment with nicotine significantly increased the levels of phosphorylated Akt. | 30345917 |
| Type | IDs |
|---|---|
| Synonymous | BTX, NARAD, nAChRa7 |
| Gene |
UniProtKB-ID:
ACHA7_RAT,
Q5UMH9_RAT
UniprotKB:
Q05941,
Q5UMH9
UniParc:
UPI0000167A95,
UPI0000451A4E
EMBL:
AABR07004078,
AABR07004075,
AABR07004079,
L31619,
AY574256,
AABR07004076,
S53987,
AY671974,
AABR07004077
Ensembl:
ENSRNOG00000010853
KO:
rno:25302
|
| Nucleutide sequences |
EMBL-CDS:
AAS90352.1,
AAB25224.2,
AAC33136.1,
AAV31080.1
Ensembl_TRS:
ENSRNOT00000051883
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000045255
RefSeq:
NP_036964.3,
XP_008757720.1
|
| Others |
UniRef100:
UniRef100_Q05941,
UniRef100_Q5UMH9
UniRef90:
UniRef90_P49582,
UniRef90_Q5UMH9
UniRef50:
UniRef50_P49582,
UniRef50_P22770
UniGene:
Rn.9698
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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