| Type | Description |
|---|---|
| Definition | fucosyltransferase 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases. | 33004438 |
| 2021-01-02 12:51:00 | The SH3 domain in the fucosyltransferase FUT8 controls FUT8 activity and localization and is essential for core fucosylation. | 32350116 |
| 2020-12-26 13:14:00 | Structural basis of substrate recognition and catalysis by fucosyltransferase 8. | 32220931 |
| 2020-09-12 16:01:00 | MicroRNA-198-5p inhibits the migration and invasion of non-small lung cancer cells by targeting fucosyltransferase 8. | 31381176 |
| 2020-05-09 10:58:00 | Report the crystal structure of FUT8 complexed with GDP and a biantennary complex N-glycan (G0), which provides insight into both substrate recognition and catalysis. FUT8 follows an SN2 mechanism and deploys a series of loops and an alpha-helix which all contribute in forming the binding site. | 32080177 |
| Type | IDs |
|---|---|
| Synonymous | CDGF, CDGF1 |
| Gene |
UniProtKB-ID:
FUT8_HUMAN,
A8K8P8_HUMAN,
Q546E0_HUMAN
UniprotKB:
Q9BYC5,
A8K8P8,
Q546E0
UniParc:
UPI00020A3E84,
UPI00015DA98B,
UPI000002A9FF,
UPI00000747B3,
UPI000000DCC9
EMBL:
Y17979,
AL359236,
AL109847,
AJ536054,
AJ514324,
AB032573,
AJ514325,
AK294242,
AJ536053,
AJ539536,
AJ536056,
AJ536055,
BC093889,
CH471061,
AL355840,
Y17976,
AB049740,
D89289,
AL161871,
AH005745,
Y17978,
Y17977,
AK292413,
AB049828,
AJ539535,
BC101816
Ensembl:
ENSG00000033170
KO:
hsa:2530
|
| Nucleutide sequences |
EMBL-CDS:
CAA76986.1,
AAI01817.1,
BAA92858.1,
BAB40929.2,
CAD55804.1,
AAB92372.2,
AAH93889.1,
BAB40975.1,
CAD55805.1,
CAA76985.1,
BAG57538.1,
CAA76987.1,
CAA76988.1,
BAA92859.2,
BAA19764.1,
BAF85102.1,
CAD62445.1,
CAD59927.1,
EAW80915.1,
CAD59925.1,
EAW80913.1,
EAW80916.1,
CAD59924.1,
EAW80917.1,
CAD59926.1,
CAD62444.1
Gene_ORFName:
hCG_22125
Ensembl_TRS:
ENST00000673929,
ENST00000394586,
ENST00000557164,
ENST00000342677,
ENST00000360689
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000345865,
ENSP00000452433,
ENSP00000501213,
ENSP00000353910,
ENSP00000378087
RefSeq:
NP_835369.1,
NP_001358463.1,
NP_001358465.1,
XP_011534916.1,
NP_004471.4,
XP_016876625.1,
NP_001358462.1,
XP_016876627.1,
XP_016876628.1,
XP_016876629.1,
NP_835368.1
|
| Others |
UniRef100:
UniRef100_Q9BYC5,
UniRef100_A8K8P8
UniRef90:
UniRef90_A8K8P8,
UniRef90_Q9BYC5
UniRef50:
UniRef50_Q9WTS2,
UniRef50_Q9BYC5
UniGene:
Hs.597649,
Hs.654961
CCDS:
CCDS9776.2,
CCDS9775.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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