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252972 Tpcn1

252972

Tpcn1

two pore channel 1

protein-coding

Mus musculus

基因描述

Type Description
Definition two pore channel 1

研究结论

Date Results Publications
2019-05-04 13:01:00 TPC1 directly interacts with syntaxins and regulates protein processing through early and recycling endosomes. 28855648
2018-08-18 10:58:00 electron cryo-microscopy structures of mouse TPC1 (MmTPC1)-a voltage-dependent, phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)-activated Na(+)-selective channel-in both the apo closed state and ligand-bound open state 29562233
2017-08-12 10:11:00 TPC1 and TPC2 were found to be essential for appropriate basal and induced autophagic flux in cardiomyocytes. 26757341
2017-03-18 11:04:00 The results confirmed the altered expression of HFABP, a key fatty acid transport protein, and of enolase and PGK1, the key enzymes in the glycolytic process 27966485
2016-09-17 10:54:00 Mice lacking the endo-lysosomal TPC1 were protected from myocardial ischemia reperfusion injury. 26395965

名称对应

Type IDs
Synonymous 5730403B01Rik, Tpc1, mKIAA1169
Gene
UniProtKB-ID: TPC1_MOUSE
UniprotKB: Q9EQJ0
UniParc: UPI0000356AD4, UPI00000274BA
EMBL: AK148129, AK077411, AF217002, AK129303, BC058951
Ensembl: ENSMUSG00000032741
KO: mmu:252972
Nucleutide sequences
EMBL-CDS: AAH58951.1, BAC98113.2, BAE43360.1, BAE28363.1, AAG44100.1
Ensembl_TRS: ENSMUST00000046426
Protein sequencees
Ensembl_PRO: ENSMUSP00000042188
RefSeq: XP_030110373.1, XP_030110374.1, NP_665852.1, XP_011246503.1
Others
UniRef100: UniRef100_Q9EQJ0
UniRef90: UniRef90_Q9EQJ0
UniRef50: UniRef50_Q9ULQ1
UniGene: Mm.114054
CCDS: CCDS39239.1

全选

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研究热度

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