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25294 Azgp1

25294

Azgp1

alpha-2-glycoprotein 1, zinc-binding

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition alpha-2-glycoprotein 1, zinc-binding

研究结论

Date Results Publications
2019-12-07 10:12:00 Insulin attenuates epileptiform discharge-induced oxidative stress by increasing zinc-alpha2-glycoprotein in primary cultured cortical neurons. 30950934
2019-04-13 10:14:00 TheZAG may inhibit TGFbeta-mediated ERK phosphorylation and inhibit neuroinflammation mediated by TNFalpha and IL-6, suggesting ZAG may suppress seizure via inhibiting neuroinflammation 29566716
2018-05-26 10:51:00 Study reports expression of Zinc-alpha2-glycoprotein (ZAG) in neurons. The level of ZAG was lower in temporal lobe epilepsy patients and time-dependently decreased in PTZ-treated rats. In addition, ZAG was shown to interact with p-ERK and TGF-beta. ZAG was found to be synthesized in neurons, and both the AZGP1 mRNA and ZAG protein levels were decreased in epilepsy patients and rat models. 28576733
2016-02-27 11:01:00 AZGP1 is a negative regulator of fibrosis progression in kidney and heart 25788525
2013-11-23 10:31:00 Overproduction of ZAG in white adipose tissue in chronic kidney disease could be a major contributor to metabolic disturbances associated with CKD. 23423258

名称对应

Type IDs
Synonymous ZA2GA, Zna2gp
Gene
UniProtKB-ID: Q3B8R6_RAT
UniprotKB: Q3B8R6
UniParc: UPI000019B600
EMBL: AABR07035540, CH474107, BC105822
Ensembl: ENSRNOG00000001333
KO: rno:25294
Nucleutide sequences
EMBL-CDS: AAI05823.1, EDL83887.1
Gene_ORFName: rCG_55974
Ensembl_TRS: ENSRNOT00000001801
Protein sequencees
Ensembl_PRO: ENSRNOP00000001801
RefSeq: XP_006249066.1, XP_006249065.1, NP_036958.2
Others
UniRef100: UniRef100_Q3B8R6
UniRef90: UniRef90_Q63678
UniRef50: UniRef50_Q64726
UniGene: Rn.5007

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

King's College London

2
2

The Second Affiliated Hospital of Chongqing Medical University

2
3

St George's Hospital, NHS Trust, London, United Kingdom (M.F., A.V., A.K., M.J.)

1
4

INIBIC-Complexo Hospitalario Universitario de A Coruña

1
5

Sidney Kimmel Medical College at Thomas Jefferson University

1
热点人员
排名 研究人员 文献
1

Lijuan Mo

3
2

Xi Liu

3
3

Xin Wei

3
4

Lifen Chen

3
5

Thomas Thum

2
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