| Type | Description |
|---|---|
| Definition | thymocyte selection-associated high mobility group box |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 11:07:00 | The VEGF-A induces the expression of transcription factor TOX in T cells to drive exhaustion-specific transcription program in T cells. | 31704735 |
| 2019-10-05 11:14:00 | TOX is a critical factor for the normal progression of T cell dysfunction and the maintenance of exhausted T cells during chronic infection, and provide a link between the suppression of effector function intrinsic to CD8 T cells and protection against immunopathology | 31207605 |
| 2019-10-05 11:14:00 | identification of the HMG-box transcription factor TOX as a central regulator of Tex cells in mice | 31207603 |
| 2019-10-05 11:14:00 | hypothesis that TOX-induced exhaustion program serves to prevent the overstimulation of T cells and activation-induced cell death in settings of chronic antigen stimulation such as cancer | 31207604 |
| 2019-02-02 12:06:00 | Results identify TOX as a transcriptional regulator of tissue-destructive CTLs in autoimmunity. | 29768177 |
| Type | IDs |
|---|---|
| Synonymous | 1700007F02Rik |
| Gene |
UniProtKB-ID:
TOX_MOUSE
UniprotKB:
Q66JW3
UniParc:
UPI0000028591,
UPI00000EB590
EMBL:
AF472514,
BC080732,
AK051947,
AK038671,
AK029694
Ensembl:
ENSMUSG00000041272
KO:
mmu:252838
|
| Nucleutide sequences |
EMBL-CDS:
BAC30091.1,
BAC26568.1,
AAL78656.1,
AAH80732.1,
BAC34818.1
Ensembl_TRS:
ENSMUST00000039987
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037966
RefSeq:
NP_001364007.1,
NP_001364008.1,
XP_017175719.1,
NP_663757.3
|
| Others |
UniRef100:
UniRef100_Q66JW3
UniRef90:
UniRef90_Q66JW3
UniRef50:
UniRef50_Q66JW3
UniGene:
Mm.435828,
Mm.488241
CCDS:
CCDS17953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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