| Type | Description |
|---|---|
| Definition | glutamate-cysteine ligase, catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 12:22:00 | Study determined the effects of troxerutin on cognitive deficits and glutamate cysteine ligase subunits (GCLM and GCLC) in the hippocampus of streptozotocin-induced type 1 diabetes mellitus rat: troxerutin alleviates oxidative stress and promotes learning potential in STZ-induced diabetic rats likely through GCL mechanisms, especially that of GCLC. | 27998794 |
| 2015-06-20 10:41:00 | in diabetic retinopathy, histone methylation at Gclc-ARE4 plays an important role in regulating the Nrf2-Gclc-GSH cascade. | 25016074 |
| 2013-11-16 12:28:00 | Increased GCLC protein expression in the lungs were observed in the rats exposed to biomass smoke and cigarette smoke. | 23682816 |
| 2012-12-29 10:02:00 | sumoylation of Nrf2 and MafG enhances heterodimerization and increases GCLC expression, which keeps HSCs in a quiescent state. | 22942279 |
| 2012-02-25 10:27:00 | After exposure to 95% oxygen accumulation of nuclear ATF4 protein in whole lung extracts coincided with induction of glutamate-cysteine ligase catalytic subunit, an intregrated stress response gene. | 21984568 |
| Type | IDs |
|---|---|
| Synonymous | Glclc |
| Gene |
UniProtKB-ID:
GSH1_RAT
UniprotKB:
P19468
UniParc:
UPI0000147FCB
EMBL:
BC081702,
J05181
Ensembl:
ENSRNOG00000006302
KO:
rno:25283
|
| Nucleutide sequences |
EMBL-CDS:
AAH81702.1,
AAA41208.1
Ensembl_TRS:
ENSRNOT00000033196
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000035540
RefSeq:
NP_036947.1
|
| Others |
UniRef100:
UniRef100_P19468
UniRef90:
UniRef90_P19468
UniRef50:
UniRef50_P19468
UniGene:
Rn.8365
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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