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25267 Pdgfra

25267

Pdgfra

platelet derived growth factor receptor alpha

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition platelet derived growth factor receptor alpha

研究结论

Date Results Publications
2019-09-21 10:23:00 CSN6 mediates PDGF-induced pulmonary arterial smooth muscle cells proliferation. 30180991
2018-10-06 11:00:00 Treatment with different concentrations of PDGF increased the levels of phosphorylated protein kinase B (AKT), beta-catenin, and Cx43, whereas inhibition of PDGFR or activation of phosphatidylinositol 3 kinase (PI3K)/AKT signaling altered b-catenin and Cx43 expression. 29174980
2017-09-09 14:08:00 overexpression in corpus cavernosum smooth muscle in rats weakened the suppressive effect of PDGFR inhibition on the morphology and phenotypic transformation induced by PDGF-BB 28245285
2016-05-21 12:39:00 PDGFs could exert their mechanism of action through an autocrine/paracrine effect on granulosa and theca cells mediated by PDGFRs. 25937181
2016-05-07 10:16:00 IL-1beta-induced MMP-9 expression is mediated through a c-Src-mediated transactivation of PDGFR/PI3K/Akt cascade linking to p47(phox)/NADPH oxidase 2 (Nox2)/reactive oxygen species signaling pathway. 25159478

名称对应

Type IDs
Synonymous APDGFR, PDGFACE
Gene
UniProtKB-ID: PGFRA_RAT, G3V6A0_RAT
UniprotKB: P20786, G3V6A0
UniParc: UPI000019B6B7, UPI0000131794
EMBL: CH473981, M63837, Z14118, AABR07014882, AABR07014881
Ensembl: ENSRNOG00000002244
KO: rno:25267
Nucleutide sequences
EMBL-CDS: AAA40743.1, CAA78488.1, EDL89926.1
Gene_ORFName: rCG_57147
Ensembl_TRS: ENSRNOT00000003077
Protein sequencees
Ensembl_PRO: ENSRNOP00000003077
RefSeq: XP_006250942.1, NP_036934.1, XP_006250941.1, XP_006250943.1
Others
UniRef100: UniRef100_P20786, UniRef100_G3V6A0
UniRef90: UniRef90_P16234
UniRef50: UniRef50_P16234
UniGene: Rn.55127

全选

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研究热度

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