例如:"NBL1", "4681", "drought"
收藏
25262 Itpr1

25262

Itpr1

inositol 1,4,5-trisphosphate receptor, type 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition inositol 1,4,5-trisphosphate receptor, type 1

研究结论

Date Results Publications
2019-10-26 11:02:00 The authors present the electron cryo-microscopy structure of InsP3R1 from rat cerebellum determined to 4.1 A resolution in the presence of activating concentrations of Ca(2+) and adenophostin A (AdA). 30470765
2018-11-10 12:05:00 IP3RI protein expression is increased in the kidney of hepatorenal syndrome rats, and may be regulated at the transcriptional level. 30090007
2018-06-09 10:10:00 These findings highlight previously unidentified functions for IP3R isoforms in the heart with specific implications for hypertrophic signaling in animal models and in human disease. 28923351
2017-08-05 11:38:00 Data suggest that proteolytic processing of Itpr1 may represent a novel form of modulation of Itpr1 channel function and increases the repertoire of Ca2+ and (protein kinase A) signaling achievable through inositol 1,4,5-trisphosphate/Itpr1 signal transduction. 28526746
2017-06-24 10:31:00 Our findings indicate that sustained SOCC activity, together with that of the sarco-endoplasmic reticulum Ca(2+)-ATPase, contribute to the maintenance of astrocytic Ca(2+) store levels, ultimately enabling astrocytic Ca(2+) signaling. 28336440

名称对应

Type IDs
Synonymous I145TR, IP3R1, InsP3R, InsP3R1, P400
Gene
UniProtKB-ID: ITPR1_RAT, C7E1V2_RAT, F1LQX8_RAT, Q5BJS8_RAT, A0A0A0MY31_RAT
UniprotKB: P29994, C7E1V2, F1LQX8, Q5BJS8, A0A0A0MY31
UniParc: UPI00004EA75B, UPI0002742D0D, UPI000002ABFC, UPI000002ABFE, UPI000002ABFD, UPI000012D7C8, UPI0002742D14, UPI000002AC00, UPI000002ABFB, UPI0001AE8008, UPI000002ABFF, UPI000002ABFA
EMBL: U38653, M64698, BC091346, U38665, GQ233032, AABR07061706, J05510, AABR07061707, M64699, AABR07061705, U38812
Ensembl: ENSRNOG00000007104
KO: rno:25262
Nucleutide sequences
EMBL-CDS: AAA41358.1, AAB51330.1, AAA41447.1, AAC53100.1, AAC53099.1, AAA41357.1, AAA41448.1, ACT21453.1, AAH91346.1
Ensembl_TRS: ENSRNOT00000064025, ENSRNOT00000041130, ENSRNOT00000043646
Protein sequencees
Ensembl_PRO: ENSRNOP00000063885, ENSRNOP00000049540, ENSRNOP00000048661
RefSeq: XP_008761397.2, XP_008761398.2, XP_006237049.1, XP_008761390.2, NP_001007236.2, XP_008761394.2, NP_001257525.1, XP_008761396.2, XP_008761399.2, XP_008761392.2, XP_008761393.2, NP_001257526.1, XP_008761389.2, XP_008761391.2, XP_008761395.2, XP_008761400.2
Others
UniRef100: UniRef100_A0A0A0MY31, UniRef100_C7E1V2, UniRef100_P29994, UniRef100_F1LNT1, UniRef100_F1LQX8
UniRef90: UniRef90_P29994-4, UniRef90_P11881
UniRef50: UniRef50_P11881
UniGene: Rn.2135

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员