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25233 Akt2

25233

Akt2

AKT serine/threonine kinase 2

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition AKT serine/threonine kinase 2

研究结论

Date Results Publications
2019-04-20 10:18:00 data identify previously unrecognized Akt2 kinase as a driver of TGFbeta induced deptor downregulation and sustained mTORC1 and mTORC2 activation. 30444896
2018-02-24 11:06:00 Suggest that when cardiomyocytes incur oxidative stress under diabetic conditions, it subsequently activates the PI3Kgamma/Akt cell-signaling pathway and further increases HMGB1 expression. 27821807
2017-06-24 11:14:00 The results of this study suggest that phosphorylation of Akt2 mediates the beneficial effects of galanin on insulin-induced glucose uptake in the adipocytes of diabetic rats. 28365702
2017-01-28 11:21:00 Data suggest that caloric restriction in aging rats up-regulates insulin-stimulated glucose uptake in the predominantly slow-twitch soleus muscle; this up-regulation appears to rely on enhanced Akt2 phosphorylation. 27786542
2016-07-16 10:42:00 Evidence links greater Akt2 activation to the caloric restriction-induced elevation of insulin-stimulated glucose uptake by muscle from old animals. 26739650

名称对应

Type IDs
Gene
UniProtKB-ID: AKT2_RAT, Q3HSE5_RAT
UniprotKB: P47197, Q3HSE5
UniParc: UPI000019C11A, UPI000012577E
EMBL: DQ198085, CH473979, D30041, AC120811
Ensembl: ENSRNOG00000018677
KO: rno:25233
Nucleutide sequences
EMBL-CDS: BAA06280.1, EDM07944.1, EDM07942.1, EDM07943.1, ABA42095.1
Gene_ORFName: rCG_53945
Ensembl_TRS: ENSRNOT00000025303
Protein sequencees
Ensembl_PRO: ENSRNOP00000025303
RefSeq: XP_017444300.1, XP_008757330.1, XP_008757332.1, XP_008757333.1, XP_008757331.1, NP_058789.1
Others
UniRef100: UniRef100_Q3HSE5, UniRef100_P47197
UniRef90: UniRef90_Q3HSE5, UniRef90_P47197
UniRef50: UniRef50_P31751, UniRef50_Q60823
UniGene: Rn.87066

全选

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研究热度

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