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25221 Sry

25221

Sry

sex determining region Y

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition sex determining region Y

研究结论

Date Results Publications
2020-03-28 12:43:00 SRY directs a previously unrecognized male-specific mechanism of dopaminergic neuron cell death. 31371505
2017-05-27 10:18:00 Chemical proteasome inhibition restored native-like SRY expression and transcriptional activity in association with restored occupancy of a sex-specific enhancer element in principal downstream gene Sox9, demonstrating that the variant SRY exhibits essentially native activity on a per molecule basis. 27576690
2016-01-30 12:00:00 These results suggest that SRY regulation of the renin-angiotensin system is partially shared with its X-chromosome homolog SOX3. 25759379
2014-07-26 12:03:00 Data show that Sry is involved in male-specific malignant conversion of rodent hepatocellular carcinoma via Sgf29 upregulation. 23893245
2013-05-18 12:03:00 Data suggest that Sry and Tcf21 (transcription factor 21) induce initial stages of embryonic Sertoli cell differentiation; Scx (scleraxis) induces later stages. This cascade--Sry>Tcf21>Scx--appears to promote subsequent sex differentiation. 23034159

名称对应

Type IDs
Synonymous SRYGENE, Sry1, Sry3BI, Tdf, Tdy
Gene
UniProtKB-ID: Q9ERV8_RAT
UniprotKB: Q9ERV8
UniParc: UPI00000E88D0
EMBL: KC215142, AY157669, FJ168067, AC243442, FJ168060, AF274872, EU984075
Ensembl: ENSRNOG00000062090
KO: rno:25221
Nucleutide sequences
EMBL-CDS: AAG09809.1, AAN37592.1, ACI29010.1, AGG39658.1, ACI00058.1, ACI29003.1
Ensembl_TRS: ENSRNOT00000092902
Protein sequencees
Ensembl_PRO: ENSRNOP00000076001
RefSeq: NP_036904.1
Others
UniRef100: UniRef100_Q9ERV8
UniRef90: UniRef90_Q8CGQ4
UniRef50: UniRef50_E0WDE4

全选

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研究热度

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