| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-31 10:39:00 | macrophages from PC1/3 KO mice and rat PC1/3-KD NR8383 macrophages secreted more pro-inflammatory cytokines such as TNF-alpha, IL6, IL1alpha and CXCL2. | 26778167 |
| 2013-12-14 10:39:00 | PC1/3 as an important regulator of vesicle trafficking and secretion in macrophages. | 23637853 |
| 2013-11-16 10:43:00 | Chronic ethanol exposure decreases prohormone convertase (pc1/3) immunoreactivity in brain. | 23050949 |
| 2010-02-08 11:15:00 | The presence of PC and GOAT in the cells, as well as n-octanoic acid in the culture medium, was necessary to produce n-octanoyl ghrelin. | 19628676 |
| 2010-01-21 00:00:00 | Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132. | 16384863 |
| Type | IDs |
|---|---|
| Synonymous | BDP, PC1, PC3 |
| Gene |
UniProtKB-ID:
NEC1_RAT
UniprotKB:
P28840
UniParc:
UPI000012FEEC
EMBL:
M76705,
M83745
Ensembl:
ENSRNOG00000011107
KO:
rno:25204
|
| Nucleutide sequences |
EMBL-CDS:
AAA40945.1,
AAA41476.1
Ensembl_TRS:
ENSRNOT00000015185
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015185
RefSeq:
NP_058787.1
|
| Others |
UniRef100:
UniRef100_P28840
UniRef90:
UniRef90_P28840
UniRef50:
UniRef50_P28840
UniGene:
Rn.11384
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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