| Type | Description |
|---|---|
| Definition | insulin-like growth factor 2 receptor |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:56:00 | The combined inhibition of the CaMKIIdelta and calcineurin signaling cascade attenuates IGF-IIR-induced cardiac hypertrophy. | 31584202 |
| 2020-02-08 12:25:00 | Finding provide evidence that IGF-IIRalpha plays a crucial role in enhancing cardiac hypertrophy under high-salt conditions. | 31211784 |
| 2019-10-05 11:04:00 | IGF-IIR predominantly induces mitophagy through the Rab9-dependent alternative autophagy. | 29574782 |
| 2018-08-18 11:15:00 | elevated glucose-induced IGF2R expression leads to enhanced IGF2R signaling cascade, which further leads to greater activation of downstream cardiac hypertrophy and apoptosis-associated effector protein molecules resulting in increased apoptosis of cardiomyocytes | 29136764 |
| 2018-05-05 11:38:00 | p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure | 28796250 |
| Type | IDs |
|---|---|
| Synonymous | IGF-IIR, Igfr2 |
| Gene |
UniProtKB-ID:
G3V824_RAT
UniprotKB:
G3V824
UniParc:
UPI0001550ABC
EMBL:
AC114389,
CH474059,
AC129234
Ensembl:
ENSRNOG00000014997
KO:
rno:25151
|
| Nucleutide sequences |
EMBL-CDS:
EDL83052.1
Gene_ORFName:
rCG_44907
Ensembl_TRS:
ENSRNOT00000021840
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000021840
RefSeq:
NP_036888.2
|
| Others |
UniRef100:
UniRef100_G3V824
UniRef90:
UniRef90_Q07113
UniRef50:
UniRef50_Q07113
UniGene:
Rn.270
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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