| Type | Description |
|---|---|
| Definition | FYN proto-oncogene, Src family tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:09:00 | Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder. | 32929078 |
| 2020-07-18 11:58:00 | leptin-signaling pathway in the hippocampus involves NR2B and Fyn | 31840160 |
| 2020-06-06 11:25:00 | Fyn gene silencing reduced the apoptosis of OLs through inhibiting the phosphorylation of ERK1/2 in epileptic model | 31852295 |
| 2019-03-30 10:21:00 | all data suggest that H2S can attenuate uranium-induced kidney cell apoptosis mediated by ER stress via 20S proteasome involving in Akt/GSK-3beta/Fyn-Nrf2 signaling axis. | 30129387 |
| 2018-09-22 10:45:00 | Fyn binds to mGluR1a at a consensus binding motif located in the intracellular C-terminus (CT) of mGluR1a in vitro. Active Fyn phosphorylates mGluR1a at a conserved tyrosine residue in the CT region. In cerebellar neurons and transfected HEK293T cells, Fyn-mediated tyrosine phosphorylation of mGluR1a is constitutively active and facilitates surface expression of mGluR1a and potentiates mGluR1a postreceptor signaling. | 28948209 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FYN_RAT,
A0A096MKC1_RAT
UniprotKB:
Q62844,
A0A096MKC1
UniParc:
UPI000017E518,
UPI00000E715E
EMBL:
AABR07045350,
AABR07045349,
U35365,
AABR07045348
Ensembl:
ENSRNOG00000000596
KO:
rno:25150
|
| Nucleutide sequences |
EMBL-CDS:
AAA82942.1
Ensembl_TRS:
ENSRNOT00000000733,
ENSRNOT00000076859
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000000733,
ENSRNOP00000068458
RefSeq:
XP_006256584.1,
XP_017457038.1,
NP_036887.1
|
| Others |
UniRef100:
UniRef100_Q62844,
UniRef100_A0A096MKC1
UniRef90:
UniRef90_H0WNS4,
UniRef90_P06241
UniRef50:
UniRef50_P06241,
UniRef50_H0WNS4
UniGene:
Rn.19361
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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