Egr4 - early growth response 4-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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25129 Egr4

基因描述

Type	Description
Definition	early growth response 4

研究结论

Date	Results	Publications
2018-09-29 11:33:00	pregulation of Egr2 and Egr4 could demote the activation of JNK/c-JUN pathway and the expression of pro-inflammatory cytokines in MCAO rats, so that Egr2 and Egr4 might be potential targets for ischemic stroke in future	29580816

名称对应

Type	IDs
Synonymous	Egr4l1, NGFI-C
Gene	UniProtKB-ID: EGR4_RAT UniprotKB: Q00911 UniParc: UPI0000129E12 EMBL: M92433, M65008 KO: rno:25129
Nucleutide sequences	EMBL-CDS: AAA41699.1, AAA41698.1
Protein sequencees	RefSeq: NP_062010.1
Others	UniRef100: UniRef100_Q00911 UniRef90: UniRef90_Q00911 UniRef50: UniRef50_Q00911 UniGene: Rn.31998

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
29580816	Overexpression of Egr2 and Egr4 protects rat brains against ischemic stroke by downregulating JNK signaling pathway. Biochimie Rui-Na Niu , Xiao-Ping Shang , Jun-Fang Teng	2018-06-01	-
23332764	DNA-binding specificities of human transcription factors. Cell Arttu Jolma , Jian Yan , Thomas Whitington , Jarkko Toivonen , Kazuhiro R Nitta , Pasi Rastas , Ekaterina Morgunova , Martin Enge , Mikko Taipale , Gonghong Wei , Kimmo Palin , Juan M Vaquerizas , Renaud Vincentelli , Nicholas M Luscombe , Timothy R Hughes , Patrick Lemaire , Esko Ukkonen , Teemu Kivioja , Jussi Taipale	2013-01-17	-
22645329	Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke. Proc. Natl. Acad. Sci. U.S.A. Manuela Mengozzi , Ilaria Cervellini , Pia Villa , ZÃ¼beyde Erbayraktar , Necati GÃ¶kmen , Osman Yilmaz , Serhat Erbayraktar , Mathini Manohasandra , Paul Van Hummelen , Peter Vandenabeele , Yuti Chernajovsky , Alexander Annenkov , Pietro Ghezzi	2012-06-12	Egr2, Egr1, Egr4, Arc
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
15060019	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Genome Res. Anne E Kwitek , Jo Gullings-Handley , Jiaming Yu , Danilo C Carlos , Kimberly Orlebeke , Jeff Nie , Jeffrey Eckert , Angela Lemke , Jaime Wendt Andrae , Susan Bromberg , Dean Pasko , Dan Chen , Todd E Scheetz , Thomas L Casavant , M Bento Soares , Val C Sheffield , Peter J Tonellato , Howard J Jacob	2004-04-01	Hoxa1, Pitpnb, Txn1, Kcnj9, Phox2a, Cga, Gjb4, Kcnc3, Nr0b2, Mgst1, Sftpb, Unc50, Acadm, Acr, Adrb2, Afp, Akt1, Aldob, Akr1b1, Apeh, Atp1a3, Atp2b2, Atp4b, Atp7b, B2m, Tspo, C4bpa, C4bpb, Calca, Calm3, Cat, Cbs, Cd53, Psg19, Chga, Chgb, Ckm, Comt, Cryaa, Cryge, Prl3b1, Ctrb1, Cyp1a1, Cyp4b1, Dbp, Ddc, Egfr, Egr1, Eno1, Ets1, Fancc, Fbp1, Fuca1, Gad2, Gfap, Gfi1, Got1, Grin2b, Nr3c1, Hbb, Hrh1, Hspa1a, Htr1a, Iapp, Ibsp, Ifnb1, Igf1, Igfbp3, Il1b, Il5, Ins1, Irf1, Klk1, Lepr, Lpl, Mbl1, Me1, Mpg, Mt1, Muc1, Ncam1, Mme, Cgref1, Cxcl10, Nos1, Nppa, Npy, Oprd1, Orm1, S100a4, Pah, Serpine1, Pgm1, Pklr, Prl6a1, Pmch, Pomc, Prkca, Pthlh
12560487	Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. Nucleic Acids Res. Eva L Decker , Nina Nehmann , Eva Kampen , Hermann Eibel , Peter F Zipfel , Christine Skerka	2003-02-01	-
1584812	Neural-specific expression, genomic structure, and chromosomal localization of the gene encoding the zinc-finger transcription factor NGFI-C. Proc. Natl. Acad. Sci. U.S.A. S D Crosby , R A Veile , H Donis-Keller , J M Baraban , R V Bhat , K S Simburger , J Milbrandt	1992-05-15	-
2072895	The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family. Mol Cell Biol S D Crosby , J J Puetz , K S Simburger , T J Fahrner , J Milbrandt	1991-08-01	-

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