| Type | Description |
|---|---|
| Definition | growth arrest and DNA-damage-inducible, alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:11:00 | Gadd45alpha affects retinal ganglion cell injury in chronic ocular hypertension rats by regulating p38MAPK pathway. | 32755658 |
| 2020-07-25 10:07:00 | The data indicated that a single bout of preconditioning exercise prior to hindlimb unloading may exert a protective effect in disuse muscle atrophy in old rats and that these effects may be partially mediated by the HDAC4/Gadd45alpha axis. | 31009659 |
| 2018-02-17 10:47:00 | A mechanism in which GADD45a is required for demethylation of the MMP-9 promoter and the induction of diabetic wound healing. The inhibition of GADD45a might be a therapeutic strategy for diabetic foot ulcers. | 29244109 |
| 2017-09-30 12:00:00 | sublytic C5b-9-induced activation of Egr-1/p300-ATF3/Gadd45 axis plays a critical role in glomerular mesangial cells apoptosis in Thy-1N rats. | 27190312 |
| 2017-08-05 11:03:00 | Growth arrest and DNA-damage-inducible protein 45 (Gadd45) is known to relieve methylation-induced gene silencing by promoting DNA demethylation. | 28346321 |
| Type | IDs |
|---|---|
| Synonymous | Ddit1, Gadd45 |
| Gene |
UniProtKB-ID:
Q66HL6_RAT
UniprotKB:
Q66HL6
UniParc:
UPI000019B8E5
EMBL:
AB102787,
AABR07060862,
CH474042,
AB102788,
BC081795
Ensembl:
ENSRNOG00000005615
KO:
rno:25112
|
| Nucleutide sequences |
EMBL-CDS:
EDL91582.1,
BAG30818.1,
BAG30819.1,
AAH81795.1
Gene_ORFName:
rCG_55338
Ensembl_TRS:
ENSRNOT00000007698
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007698
RefSeq:
NP_077041.2
|
| Others |
UniRef100:
UniRef100_Q66HL6
UniRef90:
UniRef90_P48316
UniRef50:
UniRef50_P48316
UniGene:
Rn.10250
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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