| Type | Description |
|---|---|
| Definition | pyruvate carboxylase |
| Date | Results | Publications |
|---|---|---|
| 2015-04-25 11:07:00 | Data indicate that glucose-mediated transcriptional activation of the pyruvate carboxylase (PC) gene is regulated by transcription factors. | 25054881 |
| 2013-05-04 11:38:00 | Pyruvate carboxylase and fatty acid synthase were knocked down in insulin cells. Insulin secretion, phospholipid and cholesterol esters were lowered. | 23357280 |
| 2010-03-08 12:33:00 | A carbohydrate response element in the distal gene promoter contributes to the glucose-mediated expression of pyruvate carboxylase. | 20001964 |
| 2010-01-21 00:00:00 | beta-cells activate compensatory mechanisms in response to suppression of PC expression that prevent impairment of anaplerosis, pyruvate cycling, NAPDH production, and GSIS | 16740637 |
| 2010-01-21 00:00:00 | Pyruvate carboxylase plays a role in the enhanced insulin secretion and beta-cell growth that characterize beta-cell adaptation to insulin resistance | 12147706 |
| Type | IDs |
|---|---|
| Synonymous | Pcx |
| Gene |
UniProtKB-ID:
PYC_RAT
UniprotKB:
P52873
UniParc:
UPI0000170802
EMBL:
U32314,
U36585,
BC085680
Ensembl:
ENSRNOG00000019372
KO:
rno:25104
|
| Nucleutide sequences |
EMBL-CDS:
AAC52668.1,
AAH85680.1,
AAA96256.1
Ensembl_TRS:
ENSRNOT00000082388,
ENSRNOT00000026316
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000075317,
ENSRNOP00000026316
RefSeq:
XP_006230754.1,
XP_006230751.2,
XP_006230756.1,
NP_036876.2,
XP_006230753.1,
XP_006230755.1
|
| Others |
UniRef100:
UniRef100_P52873
UniRef90:
UniRef90_P52873
UniRef50:
UniRef50_P11498
UniGene:
Rn.11094
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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