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25103 Chrnb4

25103

Chrnb4

cholinergic receptor nicotinic beta 4 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cholinergic receptor nicotinic beta 4 subunit

研究结论

Date Results Publications
2016-01-16 11:26:00 Results suggest the fast nAChR current in cutaneous dorsal root ganglia neurons was carried by homomeric alpha7 nAChRs while the slow current was carried by heteromeric (most likely alpha3beta4) nAChRs 25453771
2015-06-20 10:05:00 Four genes were significantly downregulated in the PFC [prefrontal cortex ]of SHR[spontaneously hypertensive rat ] compared to Wistar rats (Gad2, Chrnb4, Slc5a7, and Qrfpr) and none in nucleus accumbens. 25041985
2012-04-14 10:29:00 alpha6beta4* nAChRs are among the subtypes expressed by dorsal root ganglion neurons, and to our knowledge, this is the first demonstration of alpha6beta4* in neurons outside the CNS 22024738
2011-12-08 17:59:00 The role of negatively charged amino acids in the F-loop of the beta 4 subunit in channel activation and desensitization was studied using the patch-clamp technique. 18249185
2010-05-03 11:07:00 Loop 9 has a different role in the function of homomeric and heteromeric receptors. 20043866

名称对应

Type IDs
Gene
UniProtKB-ID: ACHB4_RAT
UniprotKB: P12392
UniParc: UPI0000125277, UPI000002A33B
EMBL: M89989, AY574260, X15834, M33951, U42976, M89971, J05232, M33953, M33952
Ensembl: ENSRNOG00000014427
KO: rno:25103
Nucleutide sequences
EMBL-CDS: AAA85212.1, AAS90356.1, CAA33839.1, AAA41668.1
Ensembl_TRS: ENSRNOT00000019458
Protein sequencees
Ensembl_PRO: ENSRNOP00000019458
RefSeq: NP_434693.1
Others
UniRef100: UniRef100_P12392
UniRef90: UniRef90_P12392
UniRef50: UniRef50_Q9ERK7
UniGene: Rn.9695

全选

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研究热度

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