| Type | Description |
|---|---|
| Definition | phospholipase D2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:54:00 | Increased expression of both Pld1 and Pld2 occurs simultaneously with the appearance of vascular calcification in chronic kidney disease. | 30207376 |
| 2019-03-16 11:13:00 | PLD2 toxicity is due to its lipase activity. Overexpression of a catalytically inactive mutant (K758R) of PLD2 prevents the loss of dopaminergic neurons in the substantia nigra pars compacta and does not show signs of toxicity after 10weeks of overexpression. Mutant K758R does not affect dopamine levels in the striatum. | 29526688 |
| 2012-06-23 10:45:00 | Phosphatidic acid produced by PLD2 plays an important role in regulating cell morphology in mast cells. | 22344748 |
| 2011-09-03 11:39:00 | new insights in the intricate way PLD and mTOR cooperate to control myogenesis | 21525000 |
| 2011-07-16 10:36:00 | A high level of cell invasiveness of cancer cells can be explained for the first time by combined high JAK3/PLD2 phosphorylation and activity involving PLD2's Y415 residue, which might constitute a novel target to inhibit cancer cell invasion. | 21414324 |
| Type | IDs |
|---|---|
| Synonymous | Pldc |
| Gene |
UniProtKB-ID:
PLD2_RAT
UniprotKB:
P70498
UniParc:
UPI0000131BDF
EMBL:
AB003172,
D88672
KO:
rno:25097
|
| Nucleutide sequences |
EMBL-CDS:
BAA24078.1,
BAA19882.1
|
| Protein sequencees |
RefSeq:
NP_150641.2,
XP_017452522.1
|
| Others |
UniRef100:
UniRef100_P70498
UniRef90:
UniRef90_P70498
UniRef50:
UniRef50_P70498
UniGene:
Rn.9798
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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