| Type | Description |
|---|---|
| Definition | cytochrome P450, family 2, subfamily e, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:28:00 | Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Enzyme CYP2E1 by Salicylic Acid in Rat Liver Microsomes. | 32093091 |
| 2020-04-11 12:50:00 | The differential changes in CYP2E1 in the processes of alcohol-induced and immune-mediated liver injury may result from the differential expression of inflammatory cytokines and iNOS after NF-kappaB activation, leading to the NF-kappaB-mediated transcriptional regulation of rat CYP2E1 by two independent signaling pathways. | 31881060 |
| 2019-11-09 12:11:00 | Overall, high CYP2E1 activity aggravates hepatofibrosis by restraining M2 macrophage polarization, providing a novel insight for understanding the profibrotic activity of CYP2E1 and a promising avenue for hepatofibrosis therapy. | 31116889 |
| 2018-03-03 11:31:00 | acute Formaldehyde (FA) poisoning suppressed the activities of CYP2C11, CYP2E1, and CYP3A2 and induced the activity of CYP1A2 in rats. And the change of CYP450 activity caused by acute FA poisoning may be associated with FA potential carcinogenic effects on the airways. | 28555194 |
| 2018-01-27 10:54:00 | Data suggest that combined treatment with non-nutritive sweetener aspartame and insulin in a rat model of juvenile diabetes induces CYP2E1 in neurons of cerebrum and cerebellum without modifying CYP2E1 in liver, while CYP3A2 is induced in cerebrum/cerebellum and in liver. | 25038063 |
| Type | IDs |
|---|---|
| Synonymous | Cyp2e |
| Gene |
UniProtKB-ID:
CP2E1_RAT
UniprotKB:
P05182
UniParc:
UPI0000128296
EMBL:
BC081774,
AF061442,
S48325,
J02627,
M20131
Ensembl:
ENSRNOG00000012458
KO:
rno:25086
|
| Nucleutide sequences |
EMBL-CDS:
AAC15991.1,
AAH81774.1,
AAA41060.1,
AAB24151.1,
AAA41033.1
Ensembl_TRS:
ENSRNOT00000016883
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016883
RefSeq:
NP_113731.2
|
| Others |
UniRef100:
UniRef100_P05182
UniRef90:
UniRef90_P05182
UniRef50:
UniRef50_P05181
UniGene:
Rn.1372
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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