| Type | Description |
|---|---|
| Definition | tyrosine hydroxylase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 12:02:00 | These results indicate that NT5DC2 inhibited the synthesis of dopamine by decreasing the enzymatic activity of tyrosine hydroxylase. | 31279527 |
| 2019-08-10 11:03:00 | These results indicate that dopamine or TH loss in the substantia nigra, as observed in aging, contributes as a central mechanism of reduced movement frequency. | 30056575 |
| 2019-04-27 12:15:00 | a significant reduction in expression of the dopaminergic regulation factors Nurr1 and Pitx3 could not effectively regulate TH in the VTA during chronic morphine dependence, which affects the survival of dopaminergic neurons and ultimately leads to neuronal pathology. | 30634592 |
| 2019-01-12 11:40:00 | The objective of the present study was to evaluate the effects of propolis, pollen, and caffeic acid phenethyl ester (CAPE) on tyrosine hydroxylase (TH) activity and total RNA levels of L-NAME inhibition of nitric oxide synthase in the heart, adrenal medulla, and hypothalamus of hypertensive male Sprague dawley rats | 28132600 |
| 2018-06-09 11:17:00 | In hepatic encephalopathy model rats, a reduction in TH-positive neurons was seen at both 1 and 6 months in the substantia nigra pars compacta (SNc), as well as a reduction in TH-positive fibres in the striatum. This was coincident with the appearance of alpha-synuclein-immunoreactive neurons in the SNc; some of the TH-positive neurons also showed alpha-synuclein immunoreactivity. | 28984618 |
| Type | IDs |
|---|---|
| Synonymous | The |
| Gene |
UniProtKB-ID:
TY3H_RAT
UniprotKB:
P04177
UniParc:
UPI000013786D
EMBL:
M10244,
L22651
Ensembl:
ENSRNOG00000020410
KO:
rno:25085
|
| Nucleutide sequences |
EMBL-CDS:
AAA42257.1,
AAA42258.1
Ensembl_TRS:
ENSRNOT00000027682
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000027682
RefSeq:
NP_036872.1
|
| Others |
UniRef100:
UniRef100_P04177
UniRef90:
UniRef90_P04177
UniRef50:
UniRef50_P07101-2
UniGene:
Rn.11082
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员