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25043 Eln

25043

Eln

elastin

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition elastin

研究结论

Date Results Publications
2021-02-27 13:54:00 Remodeling Matrix Synthesis in a Rat Model of Aortocaval Fistula and the Cyclic Stretch: Impaction in Pulmonary Arterial Hypertension-Congenital Heart Disease. 32630068
2020-02-15 11:14:00 Elastic fibers were found to exhibit increase in tortuosity and fragmentation with increased pregnancies. Surprisingly, secondary structure, dynamics, and crosslinking of elastin from multiparous cohorts appear similar to healthy mammalian tissues, despite fragmentation observed at the fiber level. 30914253
2019-08-03 10:07:00 Upregulation of nucleolin had an important role in Ang IIinduced vascular smooth muscle cell phenotypic transformation, and its underlying mechanism may be through interacting with tropoelastin mRNA, leading to its increased stability and protein expression. 30720050
2018-02-17 10:47:00 Overall, this study suggested that UC-MSCs could ameliorate aberrant elastin expression in the lung of hyperoxia-induced BPD model which may be associated with suppressing increased TGFbeta1 activation. 29242152
2017-08-26 10:29:00 Effects on Mmp9 and Eln mRNA expression persisted with long-term SAA treatment, resulting in decreased insoluble elastin accumulation. These data reveal a novel mechanism whereby SAA and/or infection induce changes in vascular elastin consistent with atherosclerosis. 28257481

名称对应

Type IDs
Synonymous RATTREL11, TREL11, Trela, Trela26
Gene
UniProtKB-ID: ELN_RAT, D4A9U4_RAT
UniprotKB: Q99372, D4A9U4
UniParc: UPI0000469642, UPI00005EE24E, UPI00005EE24D, UPI00005EE24F, UPI00005EE251, UPI00005EE253, UPI00005EE254, UPI00005EE250, UPI00005EE252
EMBL: M86372, M86364, M86366, AC135741, M86363, M86371, M86375, M86373, M86376, M60647, J04035, BC085910, M86355
Ensembl: ENSRNOG00000001469
KO: rno:25043
Nucleutide sequences
EMBL-CDS: AAA42271.1, AAA42269.1, AAA42272.1, AAA42268.1, AAH85910.1
Ensembl_TRS: ENSRNOT00000040069
Protein sequencees
Ensembl_PRO: ENSRNOP00000045102
RefSeq: NP_036854.1
Others
UniRef100: UniRef100_Q99372, UniRef100_D4A9U4
UniRef90: UniRef90_Q99372
UniRef50: UniRef50_P15502
UniGene: Rn.54384

全选

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