| Type | Description |
|---|---|
| Definition | insulin receptor |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:23:00 | Study found that activation of AT2R decrease insulin receptor expression and function in renal proximal tubule (RPT) cells from Wistar-Kyoto rats, whereas this inhibitory effect disturbed in RPT cells from spontaneously hypertensive rats. Results suggest that interaction between AT2R and insulin receptor may play an important role in the abnormal regulation of sodium excretion and consequently implicated in hypertension. | 29289466 |
| 2018-12-22 11:22:00 | Our data indicates that activation of IGF-1R and/or the IR autocrine loops resulting in beta-cell protection and function, involve mechanisms independent to the enhanced metabolic effects resulting from sustained GLP-1R activation. | 29412813 |
| 2018-12-22 10:09:00 | a preponderance of InsR-immunoreactivity among primary sensory neurons, which innervate visceral targets, is reported. | 29955950 |
| 2018-07-28 11:40:00 | Findings indicate functional interactions of the nociceptive ion channel transient receptor potential vanilloid type 1 receptor (TRPV1) and the insulin receptor (InsR). | 29215540 |
| 2018-03-24 11:54:00 | A single low streptozotocin (STZ) dose into the lateral ventricles of the adult rats induces wide-spread neuroinflammation in the cortical, hippocampal and hypothalamic regions and more regional-specific alterations in GLUT2 and insulin receptor (IR) protein expression, observed as early as 1 h after the treatment. GLUT2 and IR expression was altered in areas close to the site of STZ release and downstream the CSF flow. | 28470423 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
T2CB11_RAT
UniprotKB:
T2CB11
UniParc:
UPI000050144C
EMBL:
AABR07034946,
AABR07034944,
CH474084,
KF112848,
KF112847,
AABR07034945
Ensembl:
ENSRNOG00000029986
KO:
rno:24954
|
| Nucleutide sequences |
EMBL-CDS:
AGV29470.1,
AGV29469.1,
EDL74923.1
Gene_ORFName:
rCG_58966
Ensembl_TRS:
ENSRNOT00000041155
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000049655
RefSeq:
NP_058767.2
|
| Others |
UniRef100:
UniRef100_T2CB11
UniRef90:
UniRef90_P15127
UniRef50:
UniRef50_P06213
UniGene:
Rn.9876
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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