| Type | Description |
|---|---|
| Definition | ATPase copper transporting alpha |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 10:41:00 | In cultured rat aortic SMCs, PDGF stimulation rapidly promoted ATP7A association with IQGAP1 and Rac1 and their translocation to the lipid rafts and leading edge. Cotransfection assay revealed that ATP7A directly bound to NH2-terminal domain of IQGAP1 | 30257103 |
| 2014-03-08 10:40:00 | CTR1 and ATP7A play important roles in Cu transport in choroidal epithelial cells, and the Pb-induced intracellular Cu accumulation appears to be mediated, at least in part, via the alteration of CTR1 and ATP7A expression levels following Pb exposure. | 24316150 |
| 2014-03-01 11:50:00 | Atp7a knockdown in IEC-6 cells enhanced transepithelial iron flux via a novel molecular mechanism involving transcriptional induction of Fpn1 gene expression. | 24174620 |
| 2013-11-30 10:47:00 | This investigation has thus revealed a novel aspect of Atp7a gene regulation in which Sp1 may be necessary for the HIF-mediated induction of gene transcription during iron deficiency/hypoxia. | 23814049 |
| 2013-06-15 12:07:00 | Iron chelation with copper loading increased Atp7a mRNA and protein levels. | 23174565 |
| Type | IDs |
|---|---|
| Synonymous | Mnk |
| Gene |
UniProtKB-ID:
ATP7A_RAT
UniprotKB:
P70705
UniParc:
UPI00001261CB
EMBL:
U59245
Ensembl:
ENSRNOG00000061367
KO:
rno:24941
|
| Nucleutide sequences |
EMBL-CDS:
AAB06393.1
Ensembl_TRS:
ENSRNOT00000080141,
ENSRNOT00000091527
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000071625,
ENSRNOP00000073176
RefSeq:
XP_006257059.1,
NP_434690.1,
XP_008771556.1,
XP_006257057.1
|
| Others |
UniRef100:
UniRef100_P70705
UniRef90:
UniRef90_P70705
UniRef50:
UniRef50_Q04656
UniGene:
Rn.10554
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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