| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 5 group A member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:25:00 | Impact of NR5A2 and RYR2 3'UTR polymorphisms on the risk of breast cancer in a Chinese Han population. | 32572717 |
| 2020-10-03 12:51:00 | Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism. | 30923324 |
| 2020-05-09 11:03:00 | This study describes a novel and critical role of LRH-1 in T cell maturation, functions, and immopathologies and proposes LRH-1 as an emerging pharmacological target in the treatment of T cell-mediated inflammatory diseases. | 31328159 |
| 2020-04-18 11:20:00 | we have provided convincing evidence in vitro and in vivo demonstrating that Nr5a2 can induce lung CSC properties and promote tumorigenesis and progression through transcriptional up-regulation of Nanog. | 30740909 |
| 2019-12-07 12:14:00 | LRH-1-deficient adult mice fed high-fat diet displayed macrovesicular steatosis, liver injury, and glucose intolerance, all of which were reversed or improved by expressing wild-type human LRH-1. Results suggest that LRH-1 maintains the pool of arachidonoyl phospholipids, thus ensuring phospholipid diversity and normal lipid homeostasis in the adult liver. | 29515023 |
| Type | IDs |
|---|---|
| Synonymous | B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2 |
| Gene |
UniProtKB-ID:
NR5A2_HUMAN,
F1D8R9_HUMAN
UniprotKB:
O00482,
F1D8R9
UniParc:
UPI000002AF8E,
UPI0000204700,
UPI000002AF8F,
UPI0000130482
EMBL:
AK304365,
AF190464,
CH471067,
U93553,
BC118652,
BC118571,
AF146343,
AK316513,
AF124247,
U80251,
AC096633,
HQ692857
Ensembl:
ENSG00000116833
KO:
hsa:2494
|
| Nucleutide sequences |
EMBL-CDS:
AAC78727.1,
AAI18572.1,
BAG65205.1,
BAH14884.1,
EAW91306.1,
AAD37378.1,
AAG17124.1,
AAD03155.1,
AAI18653.1,
AAD26565.1,
AAG17125.1,
ADZ17368.1
Ensembl_TRS:
ENST00000236914,
ENST00000544748,
ENST00000367362
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000439116,
ENSP00000356331,
ENSP00000236914
RefSeq:
XP_011507684.1,
XP_011507682.1,
NP_003813.1,
NP_995582.1,
XP_005245119.1,
XP_011507683.1,
NP_001263393.1,
XP_016856393.1,
XP_011507686.1
|
| Others |
UniRef100:
UniRef100_O00482,
UniRef100_F1D8R9
UniRef90:
UniRef90_O00482,
UniRef90_O42101
UniRef50:
UniRef50_O00482
UniGene:
Hs.33446
CCDS:
CCDS1400.1,
CCDS1401.1,
CCDS60383.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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