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24922 Gabrb3

24922

Gabrb3

gamma-aminobutyric acid type A receptor beta 3 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition gamma-aminobutyric acid type A receptor beta 3 subunit

研究结论

Date Results Publications
2019-08-03 10:07:00 In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... 29706582
2017-07-22 11:23:00 Computational docking analysis supports the existence of a histamine binding site at the interface of homooligomeric Beta3 GABA A receptors. 27140694
2015-06-20 11:15:00 The data of this study reveal that GABAA receptor beta2 and beta3 decrease following 1 h of acute restraint stress and may play a critical role in stress-induced hyperalgesia. 24992900
2015-01-31 13:19:00 Both the Beta3 and delta containing GABA receptors have a unique ethanol binding site at the alpha4/6+Beta3-subunit interface. 24500446
2013-11-16 11:13:00 These studies identify a novel gephyrin-binding motif in GABA(A) R beta2 and beta3 large cytoplasmic loops. 23205938

名称对应

Type IDs
Gene
UniProtKB-ID: GBRB3_RAT
UniprotKB: P63079
UniParc: UPI0000004016
EMBL: X15468, L04310
KO: rno:24922
Nucleutide sequences
EMBL-CDS: AAA41180.1, CAA33495.1
Protein sequencees
RefSeq: NP_058761.2
Others
UniRef100: UniRef100_P63080
UniRef90: UniRef90_P28472
UniRef50: UniRef50_P28472
UniGene: Rn.233948

全选

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研究热度

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