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24919 Yy1

24919

Yy1

YY1 transcription factor

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition YY1 transcription factor

研究结论

Date Results Publications
2020-06-20 10:58:00 he transcription factor Yy1 regulates sST2 expression, and repression of Yy1 by metformin results in lower levels of sST2 that are associated with favorable myocardial remodeling. The manipulation of YY1 or its co-repressor HDAC4 emerge as new targets to modulate ST2/IL33 signaling and prevent adverse cardiac remodeling. 30998979
2018-05-12 10:57:00 Transcription factor YY1 was identified as one of the lead candidates regulating differentiation of rat Sertoli cells. YY1 was found to have abundant binding sites on promoters of genes upregulated during puberty. Transgenic rats with Sertoli cell specific knockdown of YY1 led to compromised spermatogenesis. 28065881
2015-12-19 11:24:00 findings suggest that NF-kappaB is a critical positive regulator of EAAT1, mediating the stimulatory effects of EGF, whereas YY1 is a negative regulator of EAAT1 with HDACs as co-repressors 26269591
2014-05-17 15:26:00 YY1, with HDACs as corepressors, is a critical negative transcriptional regulator of EAAT2 and mediates Mn-induced EAAT2 repression. 24469401
2013-10-19 14:33:00 roles of poly(ADP-ribose) polymerase-1 and transcription factor Yin Yang 1 (YY1) in Cxcl12 transcription 23555743

名称对应

Type IDs
Synonymous NF-E1, NMP-1, NMP1, UCRBP
Gene
UniProtKB-ID: Q8CHJ4_RAT
UniprotKB: Q8CHJ4
UniParc: UPI0000055E05
EMBL: AABR07065506, AB080317, AY442180
Ensembl: ENSRNOG00000004339
KO: rno:24919
Nucleutide sequences
EMBL-CDS: AAR14688.1, BAC53761.1
Ensembl_TRS: ENSRNOT00000005743
Protein sequencees
Ensembl_PRO: ENSRNOP00000005743
RefSeq: XP_006240599.1, NP_775412.1
Others
UniRef100: UniRef100_Q8CHJ4
UniRef90: UniRef90_Q8CHJ4
UniRef50: UniRef50_Q8CHJ4
UniGene: Rn.162877

全选

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研究热度

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