| Type | Description |
|---|---|
| Definition | centromere protein I |
| Date | Results | Publications |
|---|---|---|
| 2018-08-25 11:51:00 | CENPI is overexpressed in colorectal cancer (CRC) and functions as oncogene in modulating CRC cell migration, invasion and epithelial-mesenchymal transition process. | 29936263 |
| 2016-09-24 10:55:00 | CENP-C and CENP-I are key factors connecting kinetochore to CENP-A assembly. | 26527398 |
| 2015-03-07 10:40:00 | mutation in LRPAP1 is associated with high myopia. Further studies are expected to evaluate the pathogenicity of the variants in CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2. | 25525168 |
| 2014-09-27 10:59:00 | We conclude that the dual activities of Aurora B and CENP-I generate a molecular switch that maintains a robust spindle checkpoint signal at prometaphase kinetochores until they attain mature attachments to microtubules. | 24862574 |
| 2012-02-04 11:34:00 | demonstrates that CENPI, a centromere protein that localizes to the inner kinetochore structure, is a human autoantigen. The significance of anti-CENPI autoantibodies could be relevant in scleroderma patients as a marker for autoimmune liver disease | 21888900 |
| Type | IDs |
|---|---|
| Synonymous | CENP-I, FSHPRH1, LRPR1 |
| Gene |
UniProtKB-ID:
CENPI_HUMAN,
B4DZL4_HUMAN,
A0A024RCG4_HUMAN
UniprotKB:
Q92674,
B4DZL4,
A0A024RCG4
UniParc:
UPI0000073D8E,
UPI00017A843D,
UPI000004A007
EMBL:
CH471115,
AL109963,
AK302986,
BC012462,
X97249
Ensembl:
ENSG00000102384
KO:
hsa:2491
|
| Nucleutide sequences |
EMBL-CDS:
AAH12462.1,
CAA65884.1,
BAG64126.1,
EAX02841.1,
EAX02842.1,
EAX02843.1
Gene_ORFName:
hCG_1988705
Ensembl_TRS:
ENST00000372927,
ENST00000372926,
ENST00000423383
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362018,
ENSP00000399274,
ENSP00000362017
RefSeq:
XP_005262168.1,
NP_001305450.1,
NP_001305452.1,
NP_006724.2,
XP_016884872.1,
NP_001373117.1,
XP_011529197.1,
XP_011529199.1,
XP_011529201.1
|
| Others |
UniRef100:
UniRef100_Q92674,
UniRef100_B4DZL4
UniRef90:
UniRef90_Q92674
UniRef50:
UniRef50_Q92674
UniGene:
Hs.348920,
Hs.737663
CCDS:
CCDS14479.1,
CCDS83482.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员